| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 26 | 26 | 13 | 5 | 3.54 | .275 | 1.12 | 8.0 | 2.1 | 5.6 | 168.0 | 149 | 70 | 66 | 17 | 39 | 105 | 1 | 0 | 0 | 1 | 19 | 3 | 1 | 3.82 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 24 | 24 | 10 | 8 | 4.04 | .284 | 1.18 | 8.7 | 1.9 | 8.7 | 138.0 | 134 | 69 | 62 | 19 | 29 | 134 | 0 | 0 | 0 | 0 | 14 | 1 | 3 | 3.50 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 63 | 0 | 8 | 2 | 3.56 | .262 | 1.05 | 6.5 | 3.0 | 11.3 | 91.0 | 66 | 36 | 36 | 11 | 30 | 114 | 0 | 2 | 6 | 0 | 0 | 1 | 6 | 3.09 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 63 | 0 | 3 | 4 | 3.52 | .260 | 1.04 | 6.3 | 3.1 | 10.6 | 84.1 | 59 | 36 | 33 | 16 | 29 | 99 | 0 | 9 | 4 | 0 | 0 | 1 | 0 | 4.19 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 54 | 0 | 4 | 4 | 4.43 | .328 | 1.42 | 8.4 | 4.3 | 11.2 | 65.0 | 61 | 32 | 32 | 5 | 31 | 81 | 0 | 5 | 2 | 0 | 0 | 3 | 5 | 3.08 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 47 | 0 | 3 | 4 | 3.57 | .306 | 1.32 | 7.8 | 4.1 | 8.7 | 53.0 | 46 | 22 | 21 | 7 | 24 | 51 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 4.15 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 37 | 0 | 1 | 1 | 4.91 | .389 | 1.85 | 8.8 | 8.3 | 8.8 | 36.2 | 35 | 20 | 20 | 5 | 33 | 35 | 0 | 7 | 1 | 0 | 0 | 2 | 0 | 5.78 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 34 | 0 | 0 | 1 | 4.06 | .325 | 1.40 | 8.8 | 3.9 | 10.2 | 44.1 | 43 | 20 | 20 | 7 | 19 | 50 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 4.23 |
| SP | Caldwell, R.Caldwell, Ray # >> | 26 | 1914 | R | 64 | 25 | 22 | 8 | 6 | 5.18 | .331 | 1.48 | 10.6 | 2.8 | 4.8 | 116.1 | 136 | 74 | 67 | 12 | 36 | 62 | 0 | 0 | 0 | 0 | 6 | 1 | 5 | 4.23 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 20 | 1 | 5 | 4 | 3.72 | .310 | 1.32 | 9.0 | 3.0 | 8.4 | 48.1 | 48 | 23 | 20 | 9 | 16 | 45 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 4.63 |