| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 34 | 34 | 6 | 16 | 5.11 | .340 | 1.51 | 9.2 | 4.5 | 10.0 | 200.2 | 205 | 114 | 114 | 29 | 99 | 223 | 0 | 0 | 0 | 0 | 17 | 6 | 3 | 4.23 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 70 | 31 | 31 | 9 | 12 | 5.79 | .339 | 1.48 | 9.7 | 3.7 | 7.2 | 177.1 | 191 | 121 | 114 | 32 | 72 | 141 | 0 | 0 | 0 | 0 | 13 | 10 | 2 | 5.15 |
| SP | Beckett, J.Beckett, Josh # >> | 31 | 2011 | R | 58 | 31 | 31 | 12 | 11 | 4.57 | .328 | 1.44 | 9.7 | 3.2 | 6.9 | 199.0 | 215 | 116 | 101 | 30 | 71 | 153 | 0 | 0 | 0 | 0 | 14 | 5 | 6 | 4.57 |
| RP | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 92 | 0 | 8 | 6 | 3.20 | .297 | 1.26 | 7.4 | 4.0 | 9.5 | 132.0 | 108 | 47 | 47 | 9 | 58 | 139 | 0 | 8 | 2 | 0 | 0 | 1 | 2 | 3.12 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 80 | 0 | 4 | 5 | 5.90 | .353 | 1.60 | 9.9 | 4.5 | 10.6 | 97.2 | 107 | 65 | 64 | 15 | 49 | 114 | 0 | 10 | 1 | 0 | 0 | 4 | 0 | 4.30 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 62 | 68 | 0 | 4 | 5 | 5.42 | .343 | 1.53 | 9.7 | 4.1 | 9.0 | 83.0 | 89 | 51 | 50 | 13 | 38 | 83 | 0 | 8 | 5 | 0 | 0 | 3 | 5 | 4.52 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 54 | 44 | 0 | 1 | 2 | 2.87 | .238 | 0.92 | 6.3 | 2.0 | 11.4 | 53.1 | 37 | 20 | 17 | 11 | 12 | 67 | 0 | 4 | 3 | 0 | 0 | 1 | 1 | 3.91 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 47 | 40 | 0 | 5 | 1 | 5.51 | .337 | 1.52 | 10.1 | 3.7 | 8.4 | 63.2 | 71 | 39 | 39 | 10 | 26 | 59 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 4.43 |
| SP | Garrelts, S.Garrelts, Scott >> | 28 | 1989 | R | 51 | 8 | 1 | 1 | 2 | 8.36 | .432 | 2.29 | 14.8 | 5.8 | 9.0 | 14.0 | 23 | 13 | 13 | 3 | 9 | 14 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.71 |