| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 34 | 34 | 15 | 16 | 3.77 | .283 | 1.17 | 7.5 | 3.0 | 10.1 | 253.1 | 212 | 109 | 106 | 30 | 85 | 284 | 11 | 0 | 0 | 1 | 20 | 3 | 3 | 3.34 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 32 | 32 | 4 | 9 | 5.85 | .347 | 1.57 | 10.1 | 4.1 | 9.5 | 132.1 | 148 | 88 | 86 | 20 | 60 | 139 | 0 | 0 | 0 | 0 | 0 | 3 | 8 | 4.30 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 63 | 32 | 32 | 6 | 15 | 6.75 | .363 | 1.70 | 12.1 | 3.2 | 6.9 | 173.1 | 232 | 133 | 130 | 35 | 62 | 133 | 1 | 0 | 0 | 1 | 9 | 2 | 4 | 5.20 |
| SP | Eldred, C.Eldred, Cal # >> | 25 | 1992 | R | 62 | 31 | 31 | 11 | 14 | 4.86 | .333 | 1.45 | 9.7 | 3.4 | 6.1 | 214.2 | 230 | 122 | 116 | 29 | 82 | 146 | 3 | 0 | 0 | 0 | 15 | 10 | 4 | 4.69 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 83 | 0 | 7 | 7 | 4.50 | .313 | 1.33 | 7.5 | 4.4 | 10.8 | 136.0 | 114 | 70 | 68 | 17 | 67 | 163 | 0 | 5 | 3 | 0 | 0 | 5 | 0 | 3.82 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 84 | 0 | 8 | 3 | 3.11 | .296 | 1.24 | 8.0 | 3.2 | 10.0 | 118.2 | 105 | 42 | 41 | 11 | 42 | 131 | 0 | 8 | 1 | 0 | 0 | 3 | 0 | 3.14 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 58 | 0 | 2 | 2 | 3.03 | .278 | 1.13 | 7.4 | 2.8 | 8.6 | 74.1 | 61 | 25 | 25 | 6 | 23 | 71 | 0 | 7 | 1 | 0 | 0 | 2 | 4 | 3.15 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 52 | 35 | 0 | 1 | 0 | 4.65 | .371 | 1.77 | 9.9 | 6.3 | 11.9 | 40.2 | 44 | 21 | 21 | 4 | 28 | 53 | 0 | 6 | 1 | 0 | 0 | 0 | 3 | 3.75 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 47 | 2 | 0 | 0 | 0 | 9.00 | .308 | 1.33 | 12.0 | 0.0 | 6.0 | 3.0 | 4 | 3 | 3 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 54 | 22 | 0 | 4 | 6 | 5.71 | .372 | 1.76 | 10.8 | 5.0 | 6.4 | 41.0 | 49 | 29 | 26 | 5 | 23 | 29 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 4.93 |