| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 96 | 28 | 28 | 10 | 13 | 3.91 | .296 | 1.24 | 8.3 | 2.9 | 10.7 | 184.1 | 169 | 88 | 80 | 23 | 60 | 219 | 2 | 0 | 0 | 1 | 17 | 4 | 1 | 3.29 |
| SP | Flaherty, J.Flaherty, Jack # >> | 23 | 2019 | R | 83 | 27 | 27 | 8 | 12 | 5.77 | .354 | 1.62 | 10.7 | 3.9 | 8.9 | 146.2 | 174 | 101 | 94 | 20 | 64 | 144 | 0 | 0 | 0 | 0 | 10 | 3 | 8 | 4.18 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 64 | 27 | 27 | 9 | 9 | 5.23 | .339 | 1.51 | 11.0 | 2.6 | 6.8 | 179.0 | 218 | 108 | 104 | 29 | 52 | 136 | 3 | 0 | 0 | 0 | 10 | 5 | 3 | 4.54 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 59 | 26 | 26 | 9 | 12 | 5.63 | .341 | 1.51 | 11.0 | 2.6 | 6.9 | 169.1 | 207 | 108 | 106 | 23 | 49 | 129 | 6 | 0 | 0 | 0 | 12 | 7 | 1 | 4.24 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 72 | 0 | 4 | 4 | 4.18 | .311 | 1.34 | 7.5 | 4.5 | 8.5 | 103.1 | 86 | 50 | 48 | 14 | 52 | 97 | 0 | 6 | 3 | 0 | 0 | 2 | 3 | 4.46 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 71 | 0 | 3 | 1 | 2.27 | .286 | 1.15 | 6.4 | 3.9 | 10.7 | 95.0 | 68 | 28 | 24 | 6 | 41 | 113 | 0 | 10 | 2 | 0 | 0 | 5 | 0 | 2.89 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 42 | 0 | 2 | 0 | 2.41 | .286 | 1.18 | 5.7 | 5.0 | 10.2 | 52.1 | 33 | 15 | 14 | 2 | 29 | 59 | 0 | 4 | 0 | 0 | 0 | 1 | 3 | 2.96 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 49 | 28 | 0 | 2 | 1 | 5.40 | .358 | 1.67 | 8.7 | 6.7 | 12.2 | 31.2 | 30 | 21 | 19 | 2 | 23 | 42 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 3.35 |
| SP | Candelaria, J.Candelaria, John >> | 33 | 1986 | L | 54 | 16 | 0 | 3 | 2 | 2.63 | .311 | 1.35 | 9.3 | 3.0 | 6.3 | 27.1 | 28 | 9 | 8 | 4 | 9 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.52 |