| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 28 | 28 | 16 | 7 | 2.92 | .244 | 0.95 | 6.5 | 2.0 | 9.8 | 182.0 | 132 | 66 | 59 | 17 | 41 | 198 | 0 | 0 | 0 | 0 | 22 | 3 | 0 | 2.76 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 28 | 28 | 7 | 10 | 4.11 | .304 | 1.30 | 8.8 | 2.9 | 9.0 | 181.2 | 177 | 86 | 83 | 23 | 59 | 181 | 0 | 0 | 0 | 0 | 15 | 2 | 4 | 3.66 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 89 | 27 | 27 | 12 | 11 | 3.72 | .298 | 1.23 | 8.1 | 3.0 | 10.0 | 191.0 | 171 | 82 | 79 | 17 | 64 | 212 | 7 | 0 | 0 | 1 | 15 | 8 | 1 | 3.07 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 77 | 27 | 27 | 8 | 13 | 4.37 | .310 | 1.31 | 8.5 | 3.3 | 6.7 | 189.2 | 178 | 110 | 92 | 24 | 70 | 140 | 6 | 0 | 0 | 1 | 14 | 8 | 6 | 4.41 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 75 | 27 | 27 | 9 | 13 | 4.78 | .318 | 1.39 | 9.6 | 2.9 | 7.1 | 175.0 | 186 | 101 | 93 | 29 | 57 | 138 | 4 | 0 | 0 | 1 | 12 | 2 | 6 | 4.59 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 59 | 0 | 1 | 3 | 3.12 | .299 | 1.24 | 6.7 | 4.5 | 9.1 | 78.0 | 58 | 33 | 27 | 7 | 39 | 79 | 0 | 3 | 1 | 0 | 0 | 3 | 0 | 3.76 |
| RP | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 87 | 49 | 0 | 2 | 2 | 3.35 | .311 | 1.30 | 7.5 | 4.4 | 12.6 | 37.2 | 31 | 14 | 14 | 5 | 18 | 52 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.57 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 8 | 0 | 0 | 0 | 2.08 | .235 | 0.92 | 5.6 | 3.4 | 13.5 | 8.2 | 5 | 3 | 2 | 1 | 3 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.75 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 64 | 18 | 1 | 1 | 1 | 6.05 | .380 | 1.81 | 11.5 | 4.9 | 8.4 | 77.1 | 98 | 63 | 52 | 16 | 42 | 72 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.55 |
| CL | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 42 | 0 | 4 | 7 | 4.20 | .330 | 1.48 | 9.7 | 3.8 | 10.4 | 40.2 | 43 | 24 | 19 | 7 | 17 | 46 | 0 | 22 | 8 | 0 | 0 | 0 | 0 | 4.25 |