| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 35 | 35 | 13 | 10 | 2.86 | .252 | 0.98 | 6.8 | 2.1 | 9.7 | 236.0 | 177 | 77 | 75 | 27 | 55 | 255 | 4 | 0 | 0 | 1 | 24 | 6 | 5 | 3.10 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 53 | 34 | 33 | 12 | 12 | 4.91 | .341 | 1.51 | 8.5 | 5.1 | 9.3 | 172.1 | 162 | 97 | 94 | 31 | 98 | 178 | 0 | 0 | 0 | 0 | 16 | 8 | 2 | 5.12 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 32 | 31 | 7 | 8 | 5.18 | .341 | 1.53 | 8.1 | 5.7 | 10.1 | 146.0 | 131 | 85 | 84 | 24 | 92 | 164 | 0 | 0 | 0 | 0 | 11 | 4 | 5 | 4.86 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 75 | 0 | 7 | 8 | 2.64 | .279 | 1.10 | 5.7 | 4.2 | 10.8 | 85.1 | 54 | 25 | 25 | 6 | 40 | 102 | 0 | 38 | 4 | 0 | 0 | 5 | 0 | 3.11 |
| SU | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 90 | 67 | 0 | 3 | 1 | 3.36 | .264 | 1.08 | 7.1 | 2.7 | 9.5 | 88.1 | 69 | 34 | 33 | 9 | 26 | 93 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 3.10 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 96 | 0 | 8 | 2 | 4.44 | .297 | 1.26 | 7.1 | 4.3 | 9.2 | 99.1 | 78 | 49 | 49 | 11 | 47 | 101 | 0 | 3 | 7 | 0 | 0 | 1 | 0 | 3.86 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 61 | 0 | 5 | 1 | 4.21 | .354 | 1.63 | 7.3 | 7.4 | 10.9 | 62.0 | 50 | 29 | 29 | 7 | 51 | 75 | 0 | 2 | 1 | 0 | 0 | 1 | 4 | 4.56 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 76 | 49 | 0 | 2 | 4 | 3.86 | .277 | 1.15 | 6.2 | 4.2 | 7.4 | 58.1 | 40 | 25 | 25 | 9 | 27 | 48 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.76 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 41 | 0 | 3 | 2 | 5.10 | .310 | 1.35 | 6.0 | 6.2 | 10.7 | 42.1 | 28 | 24 | 24 | 7 | 29 | 50 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 4.86 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 32 | 0 | 1 | 2 | 5.35 | .348 | 1.60 | 8.2 | 6.5 | 9.3 | 33.2 | 30 | 20 | 20 | 5 | 24 | 34 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.09 |