| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 94 | 29 | 29 | 12 | 11 | 3.98 | .302 | 1.27 | 6.5 | 4.9 | 7.8 | 174.0 | 126 | 78 | 77 | 19 | 95 | 151 | 2 | 0 | 0 | 2 | 16 | 5 | 0 | 4.41 |
| SP | Gallen, Z.Gallen, Zac † >> | 26 | 2022 | R | 92 | 28 | 28 | 14 | 3 | 2.67 | .273 | 1.09 | 6.8 | 3.1 | 8.3 | 168.2 | 127 | 50 | 50 | 13 | 57 | 155 | 2 | 0 | 0 | 2 | 19 | 6 | 1 | 3.29 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 90 | 28 | 28 | 13 | 9 | 4.22 | .309 | 1.30 | 8.6 | 3.1 | 6.3 | 179.1 | 172 | 87 | 84 | 27 | 61 | 125 | 2 | 0 | 0 | 0 | 12 | 8 | 2 | 4.72 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 76 | 27 | 27 | 13 | 8 | 4.00 | .286 | 1.18 | 8.0 | 2.6 | 9.2 | 162.0 | 144 | 76 | 72 | 19 | 47 | 166 | 0 | 0 | 0 | 0 | 16 | 4 | 2 | 3.42 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 73 | 28 | 26 | 9 | 4 | 3.76 | .306 | 1.31 | 8.4 | 3.4 | 6.6 | 158.0 | 147 | 68 | 66 | 16 | 60 | 116 | 0 | 0 | 0 | 0 | 18 | 2 | 1 | 4.03 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 77 | 0 | 4 | 8 | 3.71 | .294 | 1.23 | 8.6 | 2.5 | 8.1 | 80.0 | 76 | 35 | 33 | 7 | 22 | 72 | 0 | 23 | 7 | 0 | 0 | 2 | 2 | 3.24 |
| SU | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 90 | 67 | 0 | 5 | 1 | 3.00 | .255 | 0.99 | 7.2 | 1.7 | 9.2 | 78.0 | 62 | 26 | 26 | 12 | 15 | 80 | 0 | 3 | 1 | 0 | 0 | 3 | 1 | 3.64 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 54 | 0 | 0 | 3 | 3.48 | .309 | 1.33 | 8.7 | 3.3 | 10.5 | 54.1 | 52 | 22 | 21 | 4 | 20 | 63 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 2.80 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 45 | 0 | 1 | 3 | 3.00 | .301 | 1.29 | 7.0 | 4.6 | 8.6 | 45.0 | 35 | 15 | 15 | 5 | 23 | 43 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 4.07 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 84 | 0 | 2 | 7 | 3.66 | .298 | 1.27 | 7.1 | 4.4 | 10.8 | 76.1 | 60 | 35 | 31 | 4 | 37 | 91 | 0 | 8 | 3 | 0 | 0 | 0 | 11 | 2.75 |