| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 74 | 6 | 6 | 2 | 2 | 5.54 | .333 | 1.50 | 8.5 | 5.1 | 5.6 | 37.1 | 35 | 23 | 23 | 3 | 21 | 23 | 2 | 0 | 0 | 1 | 3 | 0 | 0 | 4.51 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 6 | 6 | 2 | 4 | 6.68 | .362 | 1.64 | 11.0 | 3.9 | 5.3 | 32.1 | 39 | 24 | 24 | 6 | 14 | 19 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 5.75 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 94 | 17 | 0 | 1 | 2 | 2.76 | .258 | 0.98 | 5.6 | 3.4 | 8.4 | 16.1 | 10 | 5 | 5 | 4 | 6 | 15 | 0 | 9 | 1 | 0 | 0 | 1 | 0 | 5.69 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 17 | 0 | 2 | 0 | 4.05 | .326 | 1.45 | 7.7 | 5.4 | 9.5 | 20.0 | 17 | 10 | 9 | 3 | 12 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.65 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 16 | 0 | 0 | 1 | 5.51 | .319 | 1.41 | 10.1 | 2.8 | 11.3 | 16.1 | 18 | 10 | 10 | 6 | 5 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.31 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 9 | 0 | 2 | 1 | 3.75 | .250 | 1.00 | 5.3 | 3.8 | 14.3 | 12.0 | 7 | 5 | 5 | 3 | 5 | 19 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.33 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 3 | 0 | 0 | 0 | 3.86 | .333 | 1.50 | 11.3 | 4.5 | 11.3 | 4.2 | 5 | 2 | 2 | 2 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.50 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 8 | 0 | 0 | 0 | 3.60 | .302 | 1.30 | 6.3 | 5.4 | 11.7 | 10.0 | 7 | 4 | 4 | 1 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |