| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 21 | 21 | 10 | 8 | 3.62 | .280 | 1.17 | 8.4 | 2.2 | 4.7 | 154.0 | 143 | 67 | 62 | 13 | 37 | 80 | 6 | 0 | 0 | 2 | 13 | 0 | 3 | 3.78 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 73 | 21 | 21 | 9 | 9 | 4.20 | .303 | 1.28 | 8.5 | 3.1 | 4.9 | 167.1 | 158 | 81 | 78 | 15 | 57 | 91 | 9 | 0 | 0 | 0 | 11 | 3 | 1 | 4.16 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 19 | 19 | 6 | 7 | 4.83 | .350 | 1.57 | 9.8 | 4.3 | 3.4 | 110.0 | 120 | 62 | 59 | 11 | 53 | 42 | 0 | 0 | 0 | 0 | 10 | 5 | 1 | 5.12 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 20 | 20 | 3 | 8 | 5.55 | .372 | 1.77 | 9.2 | 6.7 | 7.9 | 94.0 | 96 | 59 | 58 | 10 | 70 | 83 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 4.88 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 20 | 19 | 8 | 7 | 4.14 | .312 | 1.34 | 8.7 | 3.4 | 5.3 | 134.2 | 130 | 67 | 62 | 17 | 51 | 79 | 7 | 0 | 0 | 1 | 10 | 2 | 4 | 4.66 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 47 | 0 | 4 | 2 | 2.64 | .273 | 1.13 | 7.5 | 2.7 | 10.2 | 61.1 | 51 | 21 | 18 | 7 | 18 | 69 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 3.11 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 44 | 0 | 3 | 3 | 3.83 | .353 | 1.62 | 7.3 | 7.3 | 7.9 | 47.0 | 38 | 21 | 20 | 6 | 38 | 41 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 5.40 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 34 | 0 | 0 | 4 | 4.29 | .288 | 1.21 | 8.8 | 2.1 | 7.3 | 42.0 | 41 | 20 | 20 | 3 | 10 | 34 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 3.02 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 24 | 1 | 3 | 4 | 4.78 | .355 | 1.63 | 10.1 | 4.6 | 5.7 | 49.0 | 55 | 27 | 26 | 6 | 25 | 31 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 4.92 |