| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 23 | 23 | 12 | 5 | 3.65 | .310 | 1.32 | 7.9 | 4.0 | 8.6 | 145.2 | 127 | 63 | 59 | 11 | 65 | 139 | 1 | 0 | 0 | 0 | 13 | 4 | 1 | 3.50 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 23 | 23 | 11 | 6 | 2.86 | .275 | 1.11 | 6.7 | 3.3 | 6.4 | 160.1 | 119 | 55 | 51 | 9 | 59 | 113 | 2 | 0 | 0 | 1 | 16 | 4 | 1 | 3.50 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 15 | 15 | 4 | 4 | 4.19 | .316 | 1.36 | 9.2 | 3.2 | 5.0 | 111.2 | 113 | 54 | 52 | 11 | 39 | 62 | 2 | 0 | 0 | 1 | 7 | 3 | 2 | 4.31 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 56 | 0 | 6 | 0 | 2.51 | .255 | 0.99 | 4.1 | 4.9 | 10.0 | 46.2 | 21 | 13 | 13 | 4 | 25 | 51 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 3.67 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 58 | 0 | 4 | 3 | 3.69 | .282 | 1.13 | 7.8 | 2.3 | 9.2 | 39.0 | 34 | 16 | 16 | 4 | 10 | 40 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.21 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 30 | 0 | 1 | 1 | 2.52 | .292 | 1.16 | 8.3 | 2.2 | 7.2 | 25.0 | 23 | 9 | 7 | 1 | 6 | 20 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 2.88 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 39 | 0 | 2 | 3 | 3.63 | .293 | 1.24 | 8.5 | 2.9 | 7.9 | 34.2 | 32 | 14 | 14 | 6 | 11 | 30 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.50 |