| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 96 | 16 | 16 | 6 | 8 | 3.26 | .284 | 1.18 | 8.2 | 2.5 | 6.9 | 118.2 | 107 | 45 | 43 | 5 | 33 | 91 | 2 | 0 | 0 | 0 | 10 | 1 | 1 | 2.87 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 16 | 16 | 5 | 7 | 5.16 | .326 | 1.43 | 10.2 | 2.8 | 7.2 | 97.2 | 110 | 58 | 56 | 15 | 30 | 78 | 2 | 0 | 0 | 0 | 7 | 2 | 1 | 4.39 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 16 | 16 | 8 | 6 | 4.56 | .294 | 1.24 | 8.7 | 2.5 | 4.0 | 106.2 | 102 | 54 | 54 | 13 | 30 | 47 | 6 | 0 | 0 | 1 | 9 | 1 | 2 | 4.58 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 16 | 16 | 6 | 4 | 4.66 | .328 | 1.44 | 10.3 | 2.6 | 4.1 | 114.0 | 131 | 63 | 59 | 14 | 33 | 52 | 4 | 0 | 0 | 0 | 8 | 3 | 4 | 4.63 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 15 | 15 | 4 | 6 | 4.94 | .368 | 1.71 | 8.8 | 6.6 | 4.6 | 82.0 | 80 | 52 | 45 | 6 | 60 | 42 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 5.23 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 41 | 0 | 5 | 0 | 1.72 | .290 | 1.18 | 7.4 | 3.3 | 8.8 | 52.1 | 43 | 11 | 10 | 1 | 19 | 51 | 0 | 4 | 0 | 0 | 0 | 2 | 3 | 2.50 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 32 | 0 | 1 | 1 | 4.58 | .352 | 1.55 | 7.8 | 6.2 | 7.6 | 39.1 | 34 | 21 | 20 | 2 | 27 | 33 | 0 | 1 | 2 | 0 | 0 | 3 | 3 | 4.28 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 32 | 0 | 3 | 0 | 5.10 | .348 | 1.53 | 10.8 | 3.0 | 9.9 | 30.0 | 36 | 18 | 17 | 1 | 10 | 33 | 0 | 3 | 1 | 0 | 0 | 2 | 2 | 2.43 |
| RP | McMahon, D.McMahon, Don >> | 37 | 1967 | R | 43 | 18 | 0 | 2 | 1 | 3.98 | .291 | 1.18 | 6.8 | 4.1 | 4.5 | 20.1 | 15 | 9 | 9 | 1 | 9 | 10 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.15 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 2 | 1 | 1 | 0 | 5.59 | .356 | 1.66 | 9.0 | 7.0 | 8.0 | 9.2 | 9 | 6 | 6 | 1 | 7 | 8 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.00 |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 52 | 10 | 0 | 0 | 2 | 11.37 | .457 | 2.53 | 18.8 | 5.3 | 2.3 | 12.2 | 25 | 16 | 16 | 3 | 7 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 7.50 |