| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 16 | 16 | 7 | 7 | 4.59 | .314 | 1.35 | 8.8 | 3.3 | 7.4 | 113.2 | 111 | 61 | 58 | 13 | 42 | 93 | 2 | 0 | 0 | 1 | 6 | 3 | 3 | 4.04 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 16 | 16 | 8 | 5 | 2.91 | .317 | 1.36 | 7.6 | 4.6 | 8.5 | 105.0 | 89 | 41 | 34 | 4 | 54 | 99 | 2 | 0 | 0 | 1 | 14 | 3 | 3 | 3.24 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 16 | 16 | 4 | 6 | 5.03 | .319 | 1.39 | 9.7 | 2.9 | 4.6 | 107.1 | 115 | 63 | 60 | 13 | 34 | 55 | 1 | 0 | 0 | 0 | 7 | 2 | 0 | 4.56 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 16 | 16 | 4 | 9 | 6.48 | .349 | 1.58 | 10.8 | 3.5 | 5.8 | 90.1 | 108 | 68 | 65 | 14 | 35 | 58 | 1 | 0 | 0 | 0 | 5 | 2 | 2 | 4.97 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 43 | 0 | 3 | 2 | 2.43 | .295 | 1.24 | 6.6 | 4.6 | 11.0 | 63.0 | 46 | 17 | 17 | 5 | 32 | 77 | 0 | 4 | 0 | 0 | 0 | 1 | 2 | 3.16 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 38 | 0 | 3 | 2 | 2.81 | .265 | 1.02 | 6.6 | 2.6 | 7.5 | 48.0 | 35 | 17 | 15 | 3 | 14 | 40 | 0 | 5 | 0 | 0 | 0 | 3 | 0 | 3.21 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 29 | 0 | 3 | 1 | 4.15 | .310 | 1.31 | 8.3 | 3.5 | 6.6 | 26.0 | 24 | 13 | 12 | 3 | 10 | 19 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.31 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 10 | 0 | 1 | 0 | 2.77 | .278 | 1.15 | 6.9 | 3.5 | 11.1 | 13.0 | 10 | 5 | 4 | 2 | 5 | 16 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.69 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 15 | 0 | 1 | 0 | 3.48 | .287 | 1.16 | 8.1 | 2.7 | 6.3 | 20.2 | 18 | 8 | 8 | 0 | 6 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.65 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 2 | 0 | 0 | 0 | 1.69 | .304 | 1.31 | 10.8 | 1.8 | 1.8 | 5.1 | 6 | 3 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.20 |