| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 22 | 22 | 12 | 2 | 2.44 | .247 | 0.96 | 6.4 | 2.3 | 8.7 | 154.2 | 110 | 44 | 42 | 7 | 39 | 149 | 0 | 0 | 0 | 0 | 18 | 3 | 0 | 2.47 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 18 | 16 | 5 | 6 | 4.50 | .336 | 1.51 | 9.1 | 4.5 | 7.2 | 106.0 | 107 | 56 | 53 | 1 | 53 | 85 | 0 | 0 | 0 | 0 | 10 | 1 | 5 | 3.05 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 20 | 20 | 7 | 7 | 3.96 | .310 | 1.33 | 7.9 | 4.1 | 6.7 | 129.2 | 113 | 58 | 57 | 10 | 59 | 96 | 0 | 0 | 0 | 0 | 10 | 3 | 1 | 3.96 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 20 | 20 | 10 | 3 | 4.68 | .305 | 1.29 | 9.2 | 2.5 | 5.0 | 134.2 | 137 | 73 | 70 | 16 | 37 | 75 | 3 | 0 | 0 | 0 | 9 | 3 | 6 | 4.33 |
| CL | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 33 | 0 | 1 | 2 | 3.67 | .270 | 1.05 | 6.9 | 2.6 | 9.3 | 34.1 | 26 | 14 | 14 | 3 | 10 | 35 | 0 | 13 | 3 | 0 | 0 | 2 | 1 | 3.15 |
| SU | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 26 | 0 | 3 | 3 | 7.43 | .337 | 1.48 | 10.2 | 3.1 | 7.4 | 23.0 | 26 | 20 | 19 | 7 | 8 | 19 | 0 | 0 | 6 | 0 | 0 | 1 | 0 | 6.48 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 47 | 0 | 4 | 1 | 3.04 | .269 | 1.09 | 6.1 | 3.7 | 8.7 | 53.1 | 36 | 19 | 18 | 5 | 22 | 51 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 3.60 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 31 | 0 | 3 | 0 | 1.38 | .228 | 0.89 | 4.8 | 3.4 | 9.3 | 32.2 | 17 | 5 | 5 | 2 | 12 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.88 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 26 | 0 | 1 | 2 | 2.67 | .283 | 1.19 | 5.3 | 5.3 | 9.3 | 27.0 | 16 | 8 | 8 | 2 | 16 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 8 | 0 | 1 | 2 | 5.85 | .382 | 1.79 | 11.0 | 5.3 | 3.7 | 32.1 | 39 | 22 | 21 | 1 | 19 | 13 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.56 |