| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 17 | 17 | 5 | 7 | 5.24 | .320 | 1.35 | 6.5 | 5.6 | 3.8 | 110.0 | 80 | 70 | 64 | 16 | 69 | 47 | 2 | 0 | 0 | 0 | 8 | 6 | 2 | 6.08 |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 30 | 17 | 17 | 3 | 8 | 7.26 | .353 | 1.64 | 10.0 | 4.8 | 6.0 | 84.1 | 93 | 68 | 68 | 13 | 45 | 56 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 5.29 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 46 | 0 | 3 | 6 | 3.92 | .265 | 0.99 | 5.1 | 3.9 | 10.1 | 57.1 | 32 | 25 | 25 | 5 | 25 | 64 | 0 | 14 | 1 | 0 | 0 | 5 | 0 | 3.47 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 49 | 0 | 1 | 2 | 2.93 | .255 | 1.01 | 7.2 | 1.9 | 8.4 | 61.1 | 49 | 20 | 20 | 4 | 13 | 57 | 0 | 2 | 5 | 0 | 0 | 1 | 0 | 2.67 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 46 | 0 | 0 | 3 | 7.04 | .383 | 1.82 | 11.7 | 4.8 | 10.3 | 47.1 | 61 | 39 | 37 | 9 | 25 | 54 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 4.91 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 37 | 0 | 3 | 2 | 4.83 | .342 | 1.54 | 7.7 | 6.1 | 7.5 | 41.0 | 35 | 23 | 22 | 3 | 28 | 34 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 4.41 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 41 | 0 | 1 | 2 | 5.18 | .327 | 1.46 | 9.6 | 3.6 | 5.2 | 74.2 | 79 | 44 | 43 | 12 | 30 | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.16 |