| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 96 | 29 | 29 | 13 | 9 | 3.80 | .279 | 1.15 | 8.0 | 2.3 | 5.0 | 225.0 | 200 | 101 | 95 | 32 | 58 | 124 | 9 | 0 | 0 | 1 | 17 | 3 | 5 | 4.56 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 28 | 28 | 9 | 12 | 5.39 | .316 | 1.37 | 10.0 | 2.3 | 4.5 | 150.1 | 167 | 96 | 90 | 20 | 39 | 75 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 4.55 |
| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 82 | 28 | 28 | 14 | 6 | 3.70 | .291 | 1.22 | 8.7 | 2.3 | 5.2 | 214.0 | 206 | 95 | 88 | 24 | 55 | 124 | 4 | 0 | 0 | 2 | 16 | 3 | 4 | 4.11 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 27 | 27 | 11 | 12 | 5.30 | .343 | 1.55 | 10.0 | 3.9 | 5.4 | 185.0 | 206 | 121 | 109 | 21 | 81 | 111 | 3 | 0 | 0 | 1 | 10 | 3 | 9 | 4.64 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 26 | 26 | 8 | 9 | 5.58 | .337 | 1.52 | 10.1 | 3.6 | 4.0 | 159.2 | 178 | 106 | 99 | 19 | 64 | 71 | 2 | 0 | 0 | 1 | 11 | 2 | 2 | 4.91 |
| RP | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 73 | 0 | 10 | 2 | 1.64 | .265 | 1.03 | 5.9 | 3.4 | 8.5 | 99.0 | 65 | 18 | 18 | 3 | 37 | 94 | 0 | 7 | 3 | 0 | 0 | 5 | 5 | 2.77 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 62 | 0 | 3 | 4 | 4.15 | .301 | 1.29 | 8.0 | 3.7 | 6.9 | 78.0 | 69 | 37 | 36 | 12 | 32 | 60 | 0 | 8 | 3 | 0 | 0 | 0 | 2 | 4.69 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 49 | 0 | 4 | 4 | 3.69 | .332 | 1.47 | 10.2 | 3.2 | 9.7 | 53.2 | 60 | 29 | 22 | 4 | 19 | 57 | 0 | 10 | 2 | 0 | 0 | 1 | 1 | 2.96 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 15 | 0 | 2 | 1 | 3.26 | .356 | 1.66 | 13.3 | 1.9 | 4.7 | 19.1 | 28 | 7 | 7 | 0 | 4 | 10 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 2.58 |