| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 25 | 25 | 12 | 9 | 4.00 | .297 | 1.24 | 7.6 | 3.6 | 4.5 | 184.2 | 156 | 87 | 82 | 14 | 73 | 93 | 6 | 0 | 0 | 2 | 12 | 5 | 2 | 4.25 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 79 | 24 | 24 | 5 | 12 | 5.29 | .336 | 1.51 | 10.7 | 3.0 | 7.6 | 149.2 | 177 | 90 | 88 | 22 | 49 | 126 | 0 | 0 | 0 | 0 | 10 | 1 | 6 | 4.23 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 24 | 24 | 10 | 7 | 3.96 | .300 | 1.28 | 8.7 | 2.8 | 4.3 | 191.0 | 184 | 90 | 84 | 17 | 60 | 91 | 11 | 0 | 0 | 0 | 11 | 2 | 0 | 4.18 |
| SP | Brown, K.Brown, Kevin # >> | 31 | 1996 | R | 56 | 23 | 22 | 9 | 9 | 4.32 | .308 | 1.32 | 9.2 | 2.7 | 5.2 | 162.2 | 166 | 82 | 78 | 10 | 48 | 93 | 6 | 0 | 0 | 0 | 10 | 3 | 11 | 3.60 |
| RP | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 66 | 0 | 4 | 4 | 2.63 | .283 | 1.17 | 6.3 | 4.3 | 6.6 | 78.2 | 55 | 23 | 23 | 8 | 37 | 57 | 0 | 11 | 6 | 0 | 0 | 1 | 2 | 4.33 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 43 | 0 | 4 | 6 | 5.24 | .335 | 1.51 | 8.6 | 5.1 | 9.8 | 46.1 | 44 | 27 | 27 | 2 | 26 | 50 | 0 | 5 | 4 | 0 | 0 | 0 | 0 | 3.09 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 36 | 0 | 2 | 1 | 2.97 | .344 | 1.55 | 7.4 | 6.7 | 9.0 | 39.1 | 32 | 13 | 13 | 4 | 29 | 39 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 4.64 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 26 | 0 | 1 | 1 | 2.51 | .317 | 1.40 | 9.6 | 3.2 | 9.0 | 28.2 | 30 | 8 | 8 | 2 | 10 | 28 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.00 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 48 | 6 | 1 | 2 | 2 | 6.65 | .350 | 1.57 | 11.1 | 3.4 | 4.3 | 21.2 | 26 | 16 | 16 | 6 | 8 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 7.05 |