| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 29 | 29 | 13 | 7 | 3.07 | .277 | 1.15 | 7.1 | 3.3 | 7.8 | 208.0 | 163 | 77 | 71 | 22 | 76 | 181 | 7 | 0 | 0 | 3 | 19 | 0 | 2 | 3.73 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 27 | 27 | 4 | 12 | 6.52 | .342 | 1.52 | 10.1 | 3.6 | 8.1 | 138.0 | 155 | 101 | 100 | 27 | 55 | 124 | 3 | 0 | 0 | 1 | 8 | 5 | 6 | 5.05 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 27 | 27 | 14 | 8 | 3.79 | .279 | 1.14 | 8.0 | 2.3 | 4.4 | 180.2 | 160 | 81 | 76 | 14 | 46 | 87 | 5 | 0 | 0 | 2 | 18 | 4 | 3 | 3.88 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 83 | 27 | 27 | 12 | 9 | 3.05 | .256 | 1.03 | 7.6 | 1.7 | 4.8 | 194.2 | 164 | 77 | 66 | 18 | 36 | 104 | 7 | 0 | 0 | 2 | 19 | 1 | 0 | 3.71 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 77 | 0 | 3 | 1 | 3.65 | .306 | 1.26 | 7.4 | 4.1 | 7.8 | 66.2 | 54 | 29 | 27 | 7 | 30 | 57 | 0 | 2 | 3 | 0 | 0 | 4 | 4 | 4.20 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 57 | 0 | 5 | 5 | 4.23 | .305 | 1.30 | 7.8 | 4.0 | 10.5 | 61.2 | 53 | 29 | 29 | 9 | 27 | 71 | 0 | 5 | 0 | 0 | 0 | 1 | 2 | 3.97 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 43 | 0 | 3 | 1 | 3.91 | .286 | 1.18 | 7.9 | 2.8 | 9.8 | 48.1 | 42 | 21 | 21 | 9 | 15 | 52 | 0 | 4 | 2 | 0 | 0 | 1 | 2 | 4.27 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 31 | 0 | 3 | 1 | 3.41 | .243 | 0.96 | 4.8 | 4.0 | 7.7 | 34.1 | 18 | 14 | 13 | 3 | 15 | 29 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 27 | 0 | 1 | 0 | 5.06 | .324 | 1.41 | 6.2 | 6.5 | 9.8 | 32.0 | 22 | 18 | 18 | 5 | 23 | 35 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.09 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 14 | 1 | 2 | 4 | 4.94 | .344 | 1.57 | 7.0 | 7.3 | 6.0 | 27.1 | 21 | 15 | 15 | 5 | 22 | 18 | 0 | 2 | 2 | 0 | 1 | 0 | 1 | 6.52 |