| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 19 | 19 | 8 | 6 | 3.07 | .262 | 1.04 | 6.9 | 2.5 | 7.9 | 149.1 | 114 | 55 | 51 | 14 | 42 | 131 | 6 | 0 | 0 | 2 | 13 | 3 | 1 | 3.37 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 18 | 18 | 5 | 3 | 5.25 | .316 | 1.38 | 9.5 | 2.9 | 4.4 | 108.0 | 114 | 65 | 63 | 22 | 35 | 53 | 4 | 0 | 0 | 1 | 8 | 1 | 1 | 5.67 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 18 | 18 | 9 | 6 | 4.44 | .319 | 1.36 | 9.3 | 3.0 | 9.2 | 119.2 | 123 | 60 | 59 | 15 | 40 | 121 | 2 | 0 | 0 | 0 | 11 | 5 | 4 | 3.74 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 77 | 18 | 18 | 10 | 5 | 4.07 | .291 | 1.19 | 8.7 | 2.1 | 6.4 | 135.0 | 130 | 62 | 61 | 12 | 31 | 96 | 4 | 0 | 0 | 0 | 9 | 5 | 3 | 3.53 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 48 | 0 | 5 | 5 | 3.90 | .241 | 0.92 | 6.3 | 2.0 | 8.4 | 60.0 | 42 | 27 | 26 | 6 | 13 | 56 | 0 | 7 | 3 | 0 | 0 | 2 | 1 | 3.18 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 33 | 0 | 0 | 2 | 2.70 | .247 | 0.98 | 5.3 | 3.8 | 10.8 | 36.2 | 21 | 11 | 11 | 1 | 15 | 43 | 0 | 9 | 0 | 0 | 0 | 0 | 0 | 2.22 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 20 | 0 | 1 | 2 | 4.34 | .378 | 1.82 | 11.5 | 5.5 | 10.0 | 18.2 | 23 | 9 | 9 | 0 | 11 | 20 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 2.61 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 9 | 0 | 0 | 3 | 7.50 | .390 | 1.92 | 9.8 | 7.5 | 9.0 | 12.0 | 13 | 10 | 10 | 4 | 10 | 12 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 7.83 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 7 | 0 | 0 | 1 | 6.52 | .310 | 1.34 | 11.0 | 2.0 | 7.0 | 9.2 | 11 | 7 | 7 | 3 | 2 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.44 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 12 | 0 | 4 | 1 | 2.93 | .285 | 1.14 | 7.3 | 3.1 | 5.8 | 67.2 | 54 | 22 | 22 | 5 | 23 | 43 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 3.90 |