| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 19 | 19 | 4 | 11 | 3.50 | .287 | 1.17 | 7.6 | 2.9 | 7.1 | 144.0 | 122 | 69 | 56 | 11 | 46 | 113 | 6 | 0 | 0 | 0 | 12 | 6 | 4 | 3.51 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 18 | 18 | 4 | 6 | 3.72 | .310 | 1.29 | 7.2 | 4.5 | 5.8 | 109.0 | 87 | 53 | 45 | 12 | 54 | 70 | 0 | 0 | 0 | 0 | 10 | 6 | 1 | 4.80 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 19 | 18 | 9 | 4 | 3.70 | .286 | 1.20 | 8.3 | 2.5 | 5.5 | 126.1 | 116 | 53 | 52 | 13 | 35 | 77 | 2 | 0 | 0 | 1 | 9 | 1 | 5 | 3.98 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 54 | 18 | 17 | 8 | 8 | 3.95 | .283 | 1.15 | 7.1 | 3.2 | 4.8 | 107.0 | 85 | 50 | 47 | 11 | 38 | 57 | 4 | 0 | 0 | 2 | 9 | 4 | 1 | 4.45 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 60 | 0 | 1 | 2 | 2.88 | .250 | 0.98 | 4.9 | 4.0 | 10.4 | 50.0 | 27 | 17 | 16 | 4 | 22 | 58 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 3.10 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 57 | 0 | 1 | 0 | 2.80 | .261 | 1.06 | 7.7 | 2.0 | 8.8 | 54.2 | 46 | 17 | 17 | 4 | 12 | 53 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 2.67 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 44 | 0 | 2 | 0 | 4.31 | .300 | 1.29 | 8.8 | 3.0 | 7.8 | 39.2 | 38 | 19 | 19 | 6 | 13 | 34 | 0 | 3 | 0 | 0 | 0 | 0 | 4 | 4.26 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 47 | 0 | 0 | 4 | 3.71 | .311 | 1.35 | 9.8 | 2.5 | 7.5 | 43.2 | 47 | 18 | 18 | 4 | 12 | 36 | 0 | 6 | 6 | 0 | 0 | 0 | 1 | 3.37 |
| RP | Williamson, S.Williamson, Scott >> | 23 | 1999 | R | 45 | 29 | 0 | 6 | 3 | 2.27 | .275 | 1.11 | 5.8 | 4.4 | 9.9 | 31.2 | 20 | 8 | 8 | 2 | 15 | 34 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.19 |