| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 31 | 31 | 18 | 4 | 2.67 | .248 | 0.98 | 6.9 | 1.9 | 9.8 | 199.0 | 153 | 60 | 59 | 13 | 43 | 217 | 2 | 0 | 0 | 1 | 23 | 1 | 0 | 2.33 |
| SP | Gibson, B.Gibson, Bob † # >> | 33 | 1968 | R | 93 | 31 | 31 | 17 | 8 | 2.94 | .263 | 1.06 | 7.2 | 2.4 | 5.6 | 217.1 | 173 | 78 | 71 | 17 | 57 | 134 | 7 | 0 | 0 | 2 | 22 | 3 | 2 | 3.61 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 29 | 29 | 12 | 6 | 4.44 | .337 | 1.49 | 8.7 | 4.7 | 7.4 | 158.0 | 153 | 89 | 78 | 19 | 83 | 130 | 0 | 0 | 0 | 0 | 14 | 5 | 3 | 4.59 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 26 | 25 | 10 | 6 | 2.97 | .274 | 1.11 | 6.1 | 3.9 | 7.5 | 157.1 | 106 | 53 | 52 | 14 | 68 | 131 | 4 | 0 | 0 | 1 | 15 | 4 | 2 | 3.87 |
| RP | Davis, W.Davis, Wade † >> | 29 | 2015 | R | 89 | 76 | 0 | 13 | 3 | 3.14 | .252 | 0.99 | 5.9 | 3.0 | 7.7 | 86.0 | 56 | 33 | 30 | 9 | 29 | 74 | 0 | 0 | 5 | 0 | 0 | 2 | 4 | 3.72 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 52 | 0 | 4 | 4 | 3.06 | .245 | 0.97 | 5.2 | 3.7 | 9.4 | 61.2 | 35 | 21 | 21 | 9 | 25 | 64 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 4.05 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 31 | 0 | 4 | 0 | 4.11 | .261 | 1.03 | 5.4 | 3.9 | 8.2 | 35.0 | 21 | 16 | 16 | 5 | 15 | 32 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.40 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 25 | 0 | 2 | 0 | 1.59 | .234 | 0.88 | 5.5 | 2.6 | 9.0 | 28.1 | 17 | 5 | 5 | 1 | 8 | 28 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 2.43 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 23 | 0 | 0 | 0 | 1.95 | .292 | 1.24 | 6.8 | 4.5 | 9.3 | 32.1 | 24 | 7 | 7 | 1 | 16 | 33 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.84 |
| SU | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 62 | 0 | 4 | 0 | 1.83 | .278 | 1.13 | 6.0 | 4.2 | 8.3 | 73.2 | 49 | 22 | 15 | 3 | 34 | 67 | 0 | 6 | 4 | 0 | 0 | 2 | 6 | 3.18 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 73 | 0 | 7 | 2 | 1.87 | .227 | 0.87 | 5.6 | 2.2 | 7.8 | 77.0 | 48 | 16 | 16 | 4 | 19 | 67 | 0 | 45 | 4 | 0 | 0 | 1 | 1 | 2.71 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 26 | 1986 | L | 10 | 11 | 1 | 1 | 2 | 7.71 | .426 | 2.19 | 14.9 | 5.1 | 5.5 | 23.1 | 38 | 20 | 20 | 2 | 13 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.74 |