| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 19 | 19 | 13 | 2 | 2.44 | .234 | 0.90 | 6.0 | 2.1 | 8.7 | 129.0 | 86 | 38 | 35 | 8 | 30 | 124 | 1 | 0 | 0 | 1 | 15 | 2 | 0 | 2.63 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 18 | 18 | 10 | 1 | 3.78 | .280 | 1.16 | 8.0 | 2.5 | 8.1 | 116.2 | 103 | 49 | 49 | 15 | 32 | 104 | 1 | 0 | 0 | 1 | 9 | 1 | 1 | 3.74 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 18 | 17 | 10 | 3 | 2.16 | .233 | 0.90 | 6.4 | 1.7 | 5.3 | 125.0 | 89 | 34 | 30 | 6 | 24 | 74 | 2 | 0 | 0 | 0 | 13 | 1 | 1 | 3.04 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 64 | 17 | 17 | 8 | 4 | 4.24 | .305 | 1.29 | 8.3 | 3.3 | 7.1 | 104.0 | 96 | 50 | 49 | 10 | 38 | 82 | 0 | 0 | 0 | 0 | 10 | 3 | 3 | 3.86 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 14 | 0 | 2 | 0 | 0.96 | .253 | 0.96 | 3.5 | 5.5 | 8.0 | 18.2 | 7 | 2 | 2 | 0 | 11 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.22 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 17 | 0 | 2 | 1 | 2.33 | .256 | 1.03 | 4.7 | 4.7 | 8.1 | 19.1 | 10 | 6 | 5 | 1 | 10 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.47 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 39 | 0 | 1 | 3 | 3.46 | .264 | 1.05 | 6.5 | 3.0 | 8.5 | 39.0 | 28 | 15 | 15 | 3 | 13 | 37 | 0 | 26 | 2 | 0 | 0 | 1 | 1 | 3.18 |
| SU | Chapman, A.Chapman, Aroldis # >> | 37 | 2025 | L | 96 | 42 | 0 | 0 | 4 | 5.31 | .339 | 1.51 | 8.1 | 5.5 | 9.7 | 39.0 | 35 | 23 | 23 | 5 | 24 | 42 | 0 | 7 | 4 | 0 | 0 | 1 | 4 | 4.44 |