| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 30 | 30 | 10 | 12 | 3.30 | .293 | 1.22 | 8.4 | 2.7 | 5.0 | 212.2 | 197 | 94 | 78 | 15 | 63 | 117 | 9 | 0 | 0 | 2 | 20 | 5 | 3 | 3.78 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 29 | 29 | 9 | 7 | 5.37 | .333 | 1.48 | 9.5 | 3.9 | 6.4 | 179.1 | 188 | 108 | 107 | 21 | 77 | 128 | 3 | 0 | 0 | 0 | 11 | 4 | 5 | 4.45 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 30 | 29 | 9 | 15 | 5.38 | .335 | 1.49 | 8.9 | 4.6 | 8.4 | 160.2 | 158 | 99 | 96 | 15 | 81 | 150 | 1 | 0 | 0 | 1 | 13 | 4 | 5 | 3.94 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 90 | 0 | 8 | 5 | 3.86 | .287 | 1.19 | 7.4 | 3.3 | 7.9 | 126.0 | 104 | 60 | 54 | 8 | 46 | 111 | 0 | 10 | 4 | 0 | 0 | 2 | 3 | 3.21 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 80 | 77 | 0 | 6 | 6 | 3.57 | .282 | 1.17 | 7.3 | 3.3 | 8.3 | 98.1 | 79 | 41 | 39 | 13 | 36 | 90 | 0 | 6 | 4 | 0 | 0 | 1 | 3 | 4.02 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 64 | 0 | 4 | 4 | 4.20 | .333 | 1.47 | 6.6 | 6.8 | 8.4 | 70.2 | 51 | 36 | 33 | 2 | 53 | 65 | 0 | 5 | 0 | 0 | 0 | 2 | 2 | 3.87 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 50 | 0 | 2 | 2 | 6.43 | .355 | 1.63 | 11.0 | 3.7 | 8.4 | 49.0 | 60 | 35 | 35 | 13 | 20 | 46 | 0 | 4 | 3 | 0 | 0 | 1 | 1 | 5.86 |