| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 31 | 31 | 5 | 20 | 5.99 | .343 | 1.54 | 9.8 | 4.1 | 8.0 | 198.1 | 215 | 141 | 132 | 28 | 91 | 175 | 3 | 0 | 0 | 2 | 10 | 4 | 6 | 4.51 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 29 | 29 | 6 | 13 | 5.18 | .326 | 1.42 | 10.0 | 2.7 | 9.3 | 191.0 | 213 | 120 | 110 | 32 | 58 | 197 | 4 | 0 | 0 | 1 | 13 | 6 | 3 | 4.12 |
| RP | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 75 | 0 | 8 | 4 | 2.93 | .296 | 1.25 | 6.2 | 5.0 | 8.8 | 126.0 | 87 | 46 | 41 | 7 | 70 | 123 | 0 | 4 | 7 | 0 | 0 | 2 | 0 | 3.48 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 71 | 0 | 5 | 7 | 2.84 | .262 | 1.02 | 8.4 | 0.8 | 6.8 | 95.0 | 89 | 33 | 30 | 9 | 8 | 72 | 0 | 6 | 6 | 0 | 0 | 4 | 0 | 3.09 |
| RP | McMahon, D.McMahon, Don >> | 37 | 1967 | R | 44 | 38 | 0 | 3 | 1 | 2.95 | .270 | 1.08 | 5.8 | 4.2 | 4.6 | 39.2 | 25 | 14 | 13 | 4 | 18 | 20 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 4.77 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 11 | 0 | 2 | 1 | 1.53 | .274 | 1.08 | 6.4 | 3.7 | 3.7 | 17.2 | 12 | 4 | 3 | 0 | 7 | 7 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.59 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 35 | 0 | 2 | 2 | 4.84 | .343 | 1.52 | 9.0 | 4.9 | 9.4 | 44.2 | 44 | 26 | 24 | 6 | 24 | 46 | 0 | 2 | 0 | 0 | 0 | 2 | 3 | 4.45 |