| SP | Jimenez, U.Jimenez, Ubaldo # >> | 26 | 2010 | R | 53 | 35 | 35 | 15 | 12 | 4.90 | .309 | 1.31 | 8.1 | 3.7 | 7.4 | 239.0 | 215 | 135 | 130 | 23 | 98 | 196 | 2 | 0 | 0 | 0 | 14 | 7 | 9 | 3.93 |
| SP | Gilbreath, L.Gilbreath, Lucas >> | 25 | 2021 | L | 46 | 42 | 41 | 0 | 3 | 4.69 | .339 | 1.51 | 9.5 | 4.3 | 6.8 | 40.1 | 42 | 22 | 21 | 4 | 19 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.30 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 42 | 31 | 31 | 2 | 6 | 5.93 | .337 | 1.51 | 8.7 | 5.0 | 7.0 | 109.1 | 105 | 72 | 72 | 18 | 60 | 85 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 5.29 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 30 | 2011 | L | 47 | 31 | 23 | 1 | 3 | 3.88 | .298 | 1.23 | 8.6 | 2.5 | 5.7 | 46.1 | 44 | 21 | 20 | 3 | 13 | 29 | 0 | 1 | 0 | 0 | 0 | 2 | 4 | 3.57 |
| CL | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 69 | 93 | 0 | 6 | 10 | 3.50 | .293 | 1.21 | 5.8 | 5.1 | 9.8 | 108.0 | 70 | 43 | 42 | 9 | 61 | 118 | 0 | 34 | 4 | 0 | 0 | 3 | 13 | 3.68 |
| RP | Bard, D.Bard, Daniel † >> | 37 | 2022 | R | 61 | 86 | 0 | 21 | 1 | 3.03 | .287 | 1.20 | 6.6 | 4.3 | 8.1 | 115.2 | 84 | 39 | 39 | 15 | 55 | 103 | 0 | 0 | 4 | 0 | 0 | 1 | 6 | 4.37 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 60 | 81 | 0 | 11 | 1 | 3.28 | .288 | 1.21 | 7.6 | 3.3 | 8.9 | 115.1 | 97 | 44 | 42 | 10 | 42 | 114 | 0 | 1 | 2 | 0 | 0 | 1 | 4 | 3.27 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 68 | 85 | 0 | 7 | 3 | 2.92 | .276 | 1.12 | 8.5 | 1.5 | 8.4 | 117.0 | 111 | 38 | 38 | 14 | 20 | 109 | 0 | 0 | 5 | 0 | 0 | 3 | 1 | 3.28 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 63 | 83 | 0 | 8 | 3 | 4.01 | .273 | 1.10 | 8.1 | 1.8 | 8.3 | 110.0 | 99 | 49 | 49 | 14 | 22 | 102 | 0 | 2 | 5 | 0 | 0 | 3 | 0 | 3.48 |
| RP | Buchholz, T.Buchholz, Taylor >> | 27 | 2008 | R | 56 | 74 | 0 | 3 | 3 | 4.17 | .330 | 1.44 | 7.9 | 5.0 | 6.0 | 82.0 | 72 | 42 | 38 | 8 | 46 | 55 | 0 | 3 | 5 | 0 | 0 | 3 | 3 | 4.72 |
| SP | Gomber, A.Gomber, Austin >> | 27 | 2021 | L | 41 | 48 | 0 | 3 | 12 | 5.44 | .377 | 1.79 | 10.1 | 6.0 | 7.0 | 96.0 | 108 | 59 | 58 | 18 | 64 | 75 | 0 | 11 | 7 | 0 | 0 | 2 | 4 | 5.94 |