| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 99 | 36 | 36 | 13 | 16 | 3.20 | .283 | 1.16 | 8.5 | 2.0 | 8.3 | 239.1 | 226 | 94 | 85 | 23 | 52 | 221 | 2 | 0 | 0 | 0 | 24 | 6 | 7 | 3.13 |
| SP | Skubal, T.Skubal, Tarik >> | 25 | 2022 | L | 83 | 35 | 35 | 11 | 9 | 5.25 | .360 | 1.66 | 11.3 | 3.6 | 8.0 | 185.0 | 232 | 119 | 108 | 17 | 75 | 165 | 0 | 0 | 0 | 0 | 10 | 5 | 4 | 3.71 |
| SP | Harnisch, P.Harnisch, Pete >> | 26 | 1992 | R | 76 | 34 | 34 | 10 | 13 | 5.30 | .346 | 1.57 | 10.0 | 4.1 | 5.5 | 192.0 | 214 | 121 | 113 | 21 | 87 | 117 | 0 | 0 | 0 | 0 | 16 | 4 | 2 | 4.63 |
| SP | Bumgarner, M.Bumgarner, Madison # >> | 21 | 2011 | L | 61 | 33 | 33 | 13 | 9 | 3.93 | .315 | 1.37 | 9.9 | 2.4 | 5.9 | 206.1 | 227 | 98 | 90 | 19 | 55 | 135 | 1 | 0 | 0 | 0 | 25 | 2 | 0 | 3.72 |
| SP | Grimes, B.Grimes, Burleigh >> | 26 | 1919 | R | 44 | 32 | 31 | 14 | 12 | 4.94 | .333 | 1.49 | 10.2 | 3.2 | 4.4 | 211.1 | 238 | 123 | 116 | 26 | 76 | 103 | 4 | 0 | 0 | 1 | 15 | 2 | 5 | 4.73 |
| RP | Quackenbush, K.Quackenbush, Kevin >> | 25 | 2014 | R | 82 | 89 | 0 | 5 | 6 | 4.33 | .346 | 1.56 | 9.0 | 5.0 | 8.9 | 104.0 | 104 | 55 | 50 | 14 | 58 | 103 | 0 | 3 | 3 | 0 | 0 | 3 | 1 | 4.53 |
| CL | Abad, F.Abad, Fernando † >> | 28 | 2014 | L | 97 | 65 | 0 | 3 | 8 | 1.90 | .243 | 0.95 | 5.9 | 2.8 | 5.4 | 75.2 | 49 | 19 | 16 | 3 | 23 | 45 | 0 | 38 | 2 | 0 | 0 | 1 | 0 | 3.28 |
| SU | Schultz, B.Schultz, Barney >> | 38 | 1964 | R | 88 | 69 | 0 | 4 | 3 | 3.99 | .313 | 1.35 | 9.3 | 2.8 | 5.5 | 79.0 | 82 | 39 | 35 | 8 | 25 | 48 | 0 | 7 | 15 | 0 | 0 | 1 | 0 | 4.09 |