| SP | Foster, R.Foster, Rube >> | 26 | 1914 | R | 47 | 9 | 9 | 2 | 4 | 4.00 | .330 | 1.43 | 10.0 | 2.9 | 5.0 | 63.0 | 70 | 32 | 28 | 6 | 20 | 35 | 1 | 0 | 0 | 0 | 5 | 3 | 1 | 4.22 |
| SP | Wakefield, T.Wakefield, Tim # >> | 37 | 2003 | R | 31 | 10 | 9 | 1 | 7 | 7.40 | .376 | 1.79 | 11.8 | 4.5 | 7.7 | 48.2 | 63 | 40 | 40 | 9 | 24 | 41 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 5.29 |
| SP | Pennock, H.Pennock, Herb >> | 26 | 1920 | L | 25 | 10 | 10 | 2 | 6 | 3.69 | .338 | 1.51 | 10.0 | 3.7 | 3.5 | 70.2 | 78 | 29 | 29 | 6 | 29 | 27 | 1 | 0 | 0 | 0 | 6 | 1 | 1 | 4.63 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 28 | 0 | 5 | 0 | 2.25 | .245 | 0.98 | 5.4 | 3.4 | 8.8 | 40.0 | 24 | 10 | 10 | 1 | 15 | 39 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.50 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 97 | 26 | 0 | 2 | 0 | 5.02 | .377 | 1.78 | 11.6 | 4.8 | 14.1 | 28.2 | 36 | 16 | 16 | 2 | 15 | 44 | 0 | 4 | 3 | 0 | 0 | 1 | 1 | 2.50 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 95 | 21 | 0 | 0 | 1 | 4.62 | .350 | 1.62 | 9.4 | 5.4 | 9.7 | 25.1 | 26 | 13 | 13 | 2 | 15 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 3.68 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 29 | 2009 | R | 24 | 18 | 0 | 1 | 2 | 4.63 | .307 | 1.29 | 7.4 | 4.3 | 7.8 | 23.1 | 19 | 13 | 12 | 3 | 11 | 20 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.52 |
| RP | Fornieles, M.Fornieles, Mike >> | 28 | 1960 | R | 16 | 15 | 0 | 0 | 2 | 4.66 | .363 | 1.71 | 9.9 | 5.7 | 8.1 | 19.1 | 21 | 10 | 10 | 2 | 12 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.47 |