| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 91 | 10 | 10 | 4 | 4 | 4.48 | .323 | 1.42 | 9.3 | 3.5 | 8.6 | 66.1 | 68 | 35 | 33 | 7 | 26 | 63 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 3.70 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 63 | 10 | 10 | 3 | 5 | 4.27 | .351 | 1.61 | 10.7 | 3.9 | 7.5 | 65.1 | 77 | 31 | 31 | 7 | 28 | 54 | 0 | 0 | 0 | 0 | 5 | 1 | 3 | 4.08 |
| SP | Gonzalez, G.Gonzalez, Gio # >> | 27 | 2012 | L | 50 | 9 | 9 | 1 | 4 | 5.02 | .333 | 1.50 | 8.5 | 5.1 | 7.7 | 57.1 | 54 | 35 | 32 | 7 | 32 | 49 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4.56 |
| SP | Zimmermann, J.Zimmermann, Jordan >> | 28 | 2014 | R | 45 | 9 | 9 | 2 | 5 | 4.15 | .278 | 1.15 | 9.2 | 1.4 | 4.5 | 60.2 | 61 | 31 | 28 | 10 | 9 | 30 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 4.62 |
| SP | Roark, T.Roark, Tanner >> | 27 | 2014 | R | 44 | 10 | 9 | 1 | 6 | 5.05 | .322 | 1.43 | 10.7 | 2.2 | 5.2 | 62.1 | 74 | 39 | 35 | 12 | 15 | 36 | 0 | 0 | 1 | 0 | 4 | 0 | 0 | 5.08 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 37 | 0 | 0 | 2 | 3.54 | .288 | 1.18 | 7.1 | 3.5 | 6.4 | 28.0 | 22 | 12 | 11 | 3 | 11 | 20 | 0 | 2 | 3 | 0 | 0 | 1 | 2 | 4.25 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 70 | 35 | 0 | 2 | 4 | 5.57 | .388 | 1.86 | 11.6 | 5.1 | 9.4 | 21.0 | 27 | 17 | 13 | 4 | 12 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.24 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 67 | 28 | 0 | 1 | 1 | 4.37 | .306 | 1.32 | 9.0 | 3.3 | 9.0 | 22.2 | 22 | 14 | 11 | 2 | 8 | 22 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 3.27 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 54 | 17 | 0 | 2 | 0 | 5.40 | .375 | 1.80 | 11.7 | 4.5 | 11.7 | 10.0 | 13 | 6 | 6 | 2 | 5 | 13 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 4.50 |
| RP | Harvey, H.Harvey, Hunter >> | 28 | 2023 | R | 43 | 9 | 0 | 0 | 0 | 3.12 | .422 | 2.19 | 12.4 | 9.0 | 9.0 | 8.2 | 11 | 3 | 3 | 1 | 8 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.63 |
| RP | Rivero, F.Rivero, Felipe >> | 23 | 2015 | L | 40 | 27 | 0 | 0 | 0 | 8.84 | .368 | 1.75 | 10.5 | 5.5 | 4.5 | 18.1 | 21 | 21 | 18 | 2 | 11 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.28 |