| SP | Jimenez, U.Jimenez, Ubaldo # >> | 26 | 2010 | R | 57 | 7 | 7 | 4 | 2 | 4.50 | .313 | 1.36 | 9.8 | 2.5 | 6.3 | 44.0 | 48 | 22 | 22 | 5 | 12 | 31 | 0 | 0 | 0 | 0 | 3 | 0 | 5 | 3.89 |
| SP | Marquez, G.Marquez, German >> | 23 | 2018 | R | 48 | 7 | 7 | 5 | 1 | 5.10 | .306 | 1.32 | 9.2 | 2.8 | 8.8 | 42.1 | 43 | 25 | 24 | 5 | 13 | 41 | 0 | 0 | 0 | 0 | 4 | 0 | 2 | 3.52 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 46 | 7 | 7 | 0 | 4 | 7.90 | .431 | 2.23 | 10.0 | 10.3 | 9.0 | 27.1 | 30 | 24 | 24 | 4 | 31 | 27 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.48 |
| SP | Gomber, A.Gomber, Austin >> | 27 | 2021 | L | 43 | 7 | 7 | 2 | 3 | 7.26 | .350 | 1.61 | 10.5 | 4.1 | 7.0 | 31.0 | 36 | 26 | 25 | 11 | 14 | 24 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 7.42 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 68 | 17 | 0 | 0 | 0 | 3.63 | .272 | 1.12 | 4.9 | 5.3 | 12.3 | 22.1 | 12 | 9 | 9 | 2 | 13 | 30 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 3.23 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 61 | 19 | 0 | 1 | 1 | 4.15 | .244 | 0.97 | 6.9 | 2.1 | 9.0 | 21.2 | 16 | 10 | 10 | 3 | 5 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.57 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 52 | 16 | 0 | 1 | 1 | 9.20 | .405 | 1.98 | 15.4 | 3.2 | 13.5 | 14.2 | 24 | 18 | 15 | 3 | 5 | 21 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.07 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 58 | 6 | 0 | 0 | 1 | 8.10 | .355 | 1.50 | 9.0 | 6.0 | 7.5 | 6.2 | 6 | 6 | 6 | 0 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.83 |