| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 35 | 35 | 17 | 10 | 2.85 | .270 | 1.09 | 7.2 | 2.5 | 8.8 | 265.0 | 213 | 85 | 84 | 16 | 75 | 258 | 10 | 0 | 0 | 1 | 26 | 6 | 1 | 2.75 |
| SP | Steele, E.Steele, Elmer >> | 22 | 1908 | R | 81 | 33 | 33 | 11 | 12 | 3.86 | .283 | 1.18 | 8.4 | 2.2 | 4.5 | 226.1 | 210 | 102 | 97 | 22 | 56 | 114 | 7 | 0 | 0 | 1 | 21 | 2 | 0 | 4.03 |
| SP | O'Brien, B.O'Brien, Buck >> | 29 | 1911 | R | 58 | 49 | 4 | 4 | 1 | 3.83 | .338 | 1.52 | 8.1 | 5.6 | 6.1 | 82.1 | 74 | 35 | 35 | 7 | 51 | 56 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.65 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 96 | 0 | 8 | 7 | 2.66 | .278 | 1.15 | 7.3 | 3.0 | 9.8 | 98.0 | 80 | 31 | 29 | 5 | 33 | 107 | 0 | 15 | 3 | 0 | 0 | 0 | 1 | 2.49 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 98 | 88 | 0 | 7 | 5 | 5.38 | .332 | 1.46 | 9.0 | 4.2 | 9.1 | 85.1 | 85 | 52 | 51 | 12 | 40 | 86 | 0 | 4 | 1 | 0 | 0 | 2 | 5 | 4.29 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 93 | 0 | 5 | 5 | 2.87 | .248 | 0.94 | 5.6 | 3.0 | 8.6 | 81.2 | 50 | 29 | 26 | 9 | 27 | 77 | 0 | 2 | 3 | 0 | 0 | 4 | 3 | 3.69 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 77 | 0 | 4 | 3 | 3.21 | .294 | 1.24 | 7.1 | 4.1 | 8.1 | 84.0 | 66 | 30 | 30 | 5 | 38 | 76 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 3.36 |
| RP | Brasier, R.Brasier, Ryan >> | 30 | 2018 | R | 76 | 45 | 0 | 2 | 2 | 3.42 | .307 | 1.33 | 9.0 | 3.1 | 6.1 | 47.1 | 47 | 22 | 18 | 3 | 16 | 32 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 3.49 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 67 | 94 | 0 | 4 | 3 | 2.29 | .243 | 0.95 | 6.0 | 2.7 | 8.9 | 74.2 | 49 | 20 | 19 | 6 | 22 | 73 | 0 | 1 | 1 | 0 | 0 | 1 | 4 | 3.01 |