| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 100 | 24 | 24 | 10 | 11 | 3.54 | .278 | 1.14 | 8.5 | 1.8 | 8.2 | 170.1 | 161 | 68 | 67 | 15 | 34 | 155 | 5 | 0 | 0 | 1 | 14 | 2 | 3 | 2.96 |
| SP | Gonsolin, T.Gonsolin, Tony >> | 28 | 2022 | R | 99 | 23 | 23 | 13 | 4 | 2.92 | .283 | 1.17 | 7.1 | 3.4 | 5.7 | 141.2 | 112 | 50 | 46 | 10 | 54 | 90 | 0 | 0 | 0 | 0 | 15 | 2 | 4 | 3.84 |
| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 97 | 23 | 23 | 0 | 2 | 3.73 | .285 | 1.20 | 9.3 | 1.6 | 7.1 | 62.2 | 64 | 26 | 26 | 2 | 11 | 49 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.37 |
| SP | Koufax, S.Koufax, Sandy >> | 27 | 1962 | L | 72 | 23 | 22 | 11 | 7 | 4.15 | .314 | 1.35 | 8.4 | 3.8 | 8.2 | 141.0 | 132 | 69 | 65 | 11 | 59 | 129 | 2 | 0 | 0 | 2 | 12 | 3 | 2 | 3.50 |
| SP | Sheehan, E.Sheehan, Emmet >> | 25 | 2025 | R | 89 | 22 | 22 | 0 | 3 | 4.36 | .324 | 1.38 | 8.8 | 3.7 | 9.3 | 53.2 | 52 | 27 | 26 | 6 | 22 | 55 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 3.81 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 98 | 63 | 0 | 7 | 0 | 1.83 | .227 | 0.87 | 6.3 | 1.6 | 10.2 | 73.2 | 51 | 15 | 15 | 2 | 13 | 83 | 0 | 1 | 3 | 0 | 0 | 1 | 2 | 1.66 |
| CL | Gagne, E.Gagne, Eric # >> | 27 | 2003 | R | 99 | 52 | 0 | 3 | 5 | 4.13 | .286 | 1.20 | 7.3 | 3.6 | 11.3 | 52.1 | 42 | 26 | 24 | 6 | 21 | 65 | 0 | 25 | 3 | 0 | 0 | 0 | 0 | 3.21 |
| RP | Almonte, Y.Almonte, Yency >> | 28 | 2022 | R | 92 | 53 | 0 | 3 | 1 | 2.07 | .258 | 1.04 | 5.7 | 3.7 | 6.5 | 65.1 | 41 | 16 | 15 | 5 | 27 | 47 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.80 |
| RP | Phillips, E.Phillips, Evan >> | 28 | 2023 | R | 88 | 40 | 0 | 6 | 2 | 3.33 | .289 | 1.22 | 8.2 | 2.7 | 7.4 | 46.0 | 42 | 17 | 17 | 3 | 14 | 38 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.11 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 79 | 34 | 0 | 1 | 1 | 0.91 | .242 | 0.93 | 5.8 | 2.8 | 9.0 | 39.2 | 25 | 4 | 4 | 1 | 12 | 39 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 2.33 |
| RP | Heaney, A.Heaney, Andrew >> | 31 | 2022 | L | 38 | 72 | 0 | 1 | 3 | 3.64 | .303 | 1.27 | 7.9 | 3.6 | 7.8 | 76.2 | 67 | 35 | 31 | 2 | 30 | 66 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 2.91 |