| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 67 | 36 | 36 | 13 | 13 | 4.78 | .321 | 1.40 | 9.5 | 3.1 | 7.9 | 218.1 | 230 | 118 | 116 | 29 | 76 | 192 | 1 | 0 | 0 | 0 | 18 | 3 | 4 | 4.06 |
| SP | Strahm, M.Strahm, Matt >> | 26 | 2018 | L | 82 | 36 | 36 | 1 | 8 | 4.26 | .311 | 1.35 | 7.7 | 4.5 | 7.8 | 74.0 | 63 | 35 | 35 | 5 | 37 | 64 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.65 |
| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 63 | 32 | 32 | 8 | 17 | 4.78 | .327 | 1.44 | 10.3 | 2.7 | 7.2 | 186.1 | 213 | 105 | 99 | 21 | 55 | 149 | 0 | 0 | 0 | 0 | 15 | 3 | 3 | 3.80 |
| SP | Paddack, C.Paddack, Chris # >> | 23 | 2019 | R | 57 | 31 | 31 | 7 | 11 | 4.38 | .312 | 1.36 | 9.5 | 2.8 | 8.4 | 174.2 | 183 | 94 | 85 | 31 | 54 | 162 | 0 | 0 | 0 | 0 | 14 | 1 | 4 | 4.40 |
| RP | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 92 | 0 | 5 | 5 | 2.26 | .271 | 1.12 | 6.4 | 3.7 | 7.8 | 135.1 | 96 | 36 | 34 | 10 | 55 | 117 | 0 | 4 | 4 | 0 | 0 | 0 | 3 | 3.45 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 94 | 88 | 0 | 8 | 0 | 2.45 | .268 | 1.09 | 6.6 | 3.2 | 8.4 | 121.0 | 89 | 34 | 33 | 10 | 43 | 113 | 0 | 6 | 2 | 0 | 0 | 1 | 2 | 3.30 |
| RP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 78 | 80 | 0 | 12 | 11 | 3.80 | .291 | 1.22 | 7.7 | 3.3 | 8.7 | 165.2 | 142 | 71 | 70 | 17 | 60 | 159 | 0 | 9 | 5 | 0 | 0 | 2 | 4 | 3.54 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 90 | 71 | 0 | 6 | 2 | 2.03 | .265 | 1.06 | 6.1 | 3.5 | 8.3 | 88.2 | 60 | 20 | 20 | 6 | 34 | 81 | 0 | 5 | 1 | 0 | 0 | 2 | 2 | 3.27 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 57 | 0 | 8 | 3 | 3.46 | .283 | 1.15 | 8.2 | 2.3 | 8.3 | 67.2 | 61 | 26 | 26 | 9 | 17 | 62 | 0 | 4 | 3 | 0 | 0 | 2 | 0 | 3.75 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 60 | 35 | 0 | 5 | 1 | 2.70 | .268 | 1.08 | 6.3 | 3.4 | 10.4 | 40.0 | 28 | 15 | 12 | 2 | 15 | 46 | 0 | 7 | 1 | 0 | 0 | 1 | 0 | 2.55 |
| RP | Luebke, C.Luebke, Cory >> | 26 | 2011 | L | 30 | 33 | 0 | 4 | 1 | 2.98 | .279 | 1.16 | 6.0 | 4.5 | 7.5 | 48.1 | 32 | 17 | 16 | 6 | 24 | 40 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 4.46 |
| RP | Adams, A.Adams, Austin >> | 30 | 2021 | R | 46 | 27 | 0 | 1 | 0 | 4.05 | .338 | 1.53 | 7.9 | 6.0 | 9.0 | 33.1 | 29 | 15 | 15 | 1 | 22 | 33 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.39 |