| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 85 | 24 | 24 | 11 | 7 | 3.34 | .288 | 1.18 | 8.6 | 2.1 | 5.6 | 183.1 | 175 | 73 | 68 | 10 | 42 | 114 | 10 | 0 | 0 | 3 | 14 | 5 | 5 | 3.23 |
| SP | Skubal, T.Skubal, Tarik # >> | 28 | 2025 | L | 92 | 23 | 23 | 12 | 4 | 3.98 | .281 | 1.16 | 8.6 | 1.9 | 8.8 | 144.2 | 138 | 64 | 64 | 17 | 30 | 140 | 1 | 0 | 0 | 0 | 13 | 2 | 3 | 3.26 |
| SP | Verlander, J.Verlander, Justin >> | 28 | 2011 | R | 87 | 24 | 23 | 11 | 5 | 4.32 | .305 | 1.31 | 9.4 | 2.5 | 6.3 | 154.1 | 160 | 75 | 74 | 18 | 42 | 108 | 6 | 0 | 0 | 2 | 12 | 1 | 7 | 3.95 |
| SP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 84 | 25 | 23 | 0 | 2 | 4.66 | .353 | 1.62 | 11.5 | 3.1 | 6.5 | 58.0 | 74 | 34 | 30 | 3 | 20 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.31 |
| SP | Garcia, R.Garcia, Rony >> | 24 | 2022 | R | 64 | 22 | 21 | 0 | 5 | 3.84 | .340 | 1.51 | 9.7 | 3.8 | 5.5 | 75.0 | 81 | 39 | 32 | 10 | 32 | 46 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 4.91 |
| RP | Turnbull, S.Turnbull, Spencer † >> | 28 | 2021 | R | 54 | 63 | 0 | 14 | 1 | 3.75 | .290 | 1.20 | 8.0 | 2.8 | 7.0 | 112.2 | 100 | 52 | 47 | 14 | 35 | 87 | 0 | 3 | 5 | 0 | 0 | 3 | 0 | 4.09 |
| RP | Greene, S.Greene, Shane † >> | 30 | 2019 | R | 90 | 57 | 0 | 7 | 5 | 3.22 | .295 | 1.22 | 7.4 | 3.6 | 8.7 | 67.0 | 55 | 30 | 24 | 5 | 27 | 65 | 0 | 8 | 5 | 0 | 0 | 2 | 0 | 3.33 |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 72 | 45 | 0 | 2 | 0 | 4.22 | .350 | 1.57 | 9.7 | 4.4 | 8.6 | 49.0 | 53 | 28 | 23 | 5 | 24 | 47 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 4.00 |
| RP | Miller, S.Miller, Shelby >> | 33 | 2024 | R | 51 | 38 | 0 | 3 | 5 | 4.44 | .308 | 1.29 | 8.4 | 3.4 | 6.8 | 48.2 | 45 | 27 | 24 | 4 | 18 | 36 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 3.83 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 76 | 41 | 0 | 6 | 2 | 4.76 | .332 | 1.46 | 9.3 | 3.9 | 7.3 | 62.1 | 64 | 35 | 33 | 7 | 27 | 50 | 0 | 5 | 2 | 0 | 0 | 2 | 8 | 4.26 |