| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 67 | 10 | 10 | 5 | 3 | 3.49 | .304 | 1.28 | 9.3 | 2.3 | 9.3 | 67.0 | 69 | 26 | 26 | 7 | 17 | 69 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 3.15 |
| SP | Strahm, M.Strahm, Matt >> | 26 | 2018 | L | 81 | 10 | 10 | 1 | 0 | 1.01 | .223 | 0.86 | 4.8 | 3.1 | 8.7 | 26.2 | 14 | 3 | 3 | 1 | 9 | 25 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2.62 |
| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 63 | 10 | 10 | 2 | 7 | 3.69 | .314 | 1.36 | 9.3 | 3.0 | 7.0 | 63.1 | 65 | 28 | 26 | 8 | 21 | 49 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 4.14 |
| SP | Paddack, C.Paddack, Chris >> | 23 | 2019 | R | 56 | 10 | 10 | 1 | 5 | 5.08 | .344 | 1.57 | 10.6 | 3.7 | 8.2 | 56.2 | 66 | 32 | 32 | 14 | 23 | 51 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 5.66 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 94 | 24 | 0 | 1 | 0 | 1.99 | .312 | 1.36 | 7.5 | 4.9 | 8.7 | 31.2 | 26 | 7 | 7 | 1 | 17 | 30 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.13 |
| RP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 78 | 23 | 0 | 5 | 6 | 3.99 | .290 | 1.23 | 8.2 | 2.9 | 9.4 | 47.1 | 43 | 22 | 21 | 7 | 15 | 49 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 3.81 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 90 | 19 | 0 | 1 | 1 | 2.45 | .252 | 1.01 | 7.6 | 1.8 | 7.2 | 25.2 | 21 | 7 | 7 | 1 | 5 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.52 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 16 | 0 | 4 | 0 | 3.78 | .333 | 1.50 | 11.3 | 2.8 | 9.0 | 16.2 | 20 | 7 | 7 | 1 | 5 | 16 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 2.75 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 60 | 7 | 0 | 0 | 0 | 2.25 | .273 | 1.13 | 6.8 | 3.4 | 10.1 | 8.0 | 6 | 2 | 2 | 1 | 3 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| RP | Luebke, C.Luebke, Cory >> | 26 | 2011 | L | 30 | 7 | 0 | 1 | 0 | 0.00 | .147 | 0.52 | 3.0 | 2.0 | 5.0 | 9.2 | 3 | 0 | 0 | 0 | 2 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.56 |
| RP | Adams, A.Adams, Austin >> | 30 | 2021 | R | 46 | 5 | 0 | 1 | 0 | 2.25 | .314 | 1.38 | 4.5 | 7.9 | 5.6 | 8.0 | 4 | 2 | 2 | 0 | 7 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.38 |