| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 89 | 27 | 27 | 1 | 7 | 3.81 | .330 | 1.45 | 8.1 | 5.0 | 10.2 | 82.2 | 74 | 43 | 35 | 6 | 46 | 93 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 3.44 |
| SP | Wesneski, H.Wesneski, Hayden >> | 24 | 2022 | R | 79 | 25 | 25 | 0 | 2 | 3.65 | .321 | 1.41 | 8.9 | 3.8 | 8.5 | 79.0 | 78 | 35 | 32 | 5 | 33 | 75 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.22 |
| SP | Ramsdell, W.Ramsdell, Willie >> | 36 | 1952 | R | 75 | 25 | 25 | 0 | 4 | 3.39 | .334 | 1.51 | 8.3 | 5.3 | 4.8 | 77.0 | 71 | 41 | 29 | 7 | 45 | 41 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.87 |
| SP | Darvish, Y.Darvish, Yu # >> | 33 | 2020 | R | 73 | 24 | 20 | 1 | 4 | 6.16 | .357 | 1.66 | 12.2 | 2.8 | 9.1 | 64.1 | 87 | 47 | 44 | 11 | 20 | 65 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.14 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 33 | 2021 | R | 100 | 70 | 0 | 9 | 0 | 2.17 | .281 | 1.14 | 5.5 | 4.8 | 9.8 | 87.0 | 53 | 29 | 21 | 4 | 46 | 95 | 0 | 4 | 2 | 0 | 0 | 3 | 5 | 3.10 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 97 | 67 | 0 | 15 | 0 | 2.24 | .266 | 1.05 | 5.9 | 3.6 | 11.0 | 96.1 | 63 | 28 | 24 | 12 | 38 | 117 | 0 | 2 | 1 | 0 | 0 | 4 | 8 | 3.50 |
| RP | Tepera, R.Tepera, Ryan >> | 33 | 2021 | R | 92 | 65 | 0 | 9 | 3 | 2.63 | .275 | 1.13 | 6.6 | 3.6 | 9.2 | 92.1 | 67 | 31 | 27 | 3 | 37 | 94 | 0 | 5 | 3 | 0 | 0 | 1 | 1 | 2.62 |
| RP | Hodge, P.Hodge, Porter >> | 23 | 2024 | R | 78 | 60 | 0 | 13 | 2 | 2.35 | .248 | 0.98 | 5.3 | 3.5 | 9.1 | 88.0 | 52 | 31 | 23 | 5 | 34 | 89 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.91 |
| RP | Strop, P.Strop, Pedro # >> | 31 | 2016 | R | 73 | 61 | 0 | 7 | 2 | 3.28 | .247 | 0.94 | 5.8 | 2.7 | 8.9 | 90.2 | 58 | 36 | 33 | 10 | 27 | 89 | 0 | 4 | 2 | 0 | 0 | 4 | 7 | 3.50 |
| RP | Miller, T.Miller, Tyson >> | 28 | 2024 | R | 70 | 40 | 0 | 9 | 3 | 4.40 | .279 | 1.16 | 8.1 | 2.4 | 5.5 | 59.1 | 53 | 30 | 29 | 6 | 16 | 36 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.92 |
| SP | Pfiester, J.Pfiester, Jack >> | 29 | 1907 | L | 62 | 32 | 7 | 6 | 5 | 4.50 | .309 | 1.33 | 8.4 | 3.6 | 4.3 | 90.0 | 84 | 55 | 45 | 8 | 36 | 43 | 0 | 3 | 1 | 0 | 3 | 1 | 2 | 4.43 |
| SP | Brown, M.Brown, Mordecai # >> | 28 | 1904 | R | 68 | 61 | 7 | 12 | 8 | 3.82 | .281 | 1.14 | 8.1 | 2.2 | 4.8 | 157.2 | 141 | 76 | 67 | 20 | 39 | 84 | 6 | 11 | 5 | 0 | 5 | 5 | 5 | 4.43 |