| SP | Roark, T.Roark, Tanner >> | 26 | 2013 | R | 89 | 6 | 6 | 0 | 0 | 6.55 | .340 | 1.45 | 10.6 | 2.5 | 3.3 | 11.0 | 13 | 8 | 8 | 1 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.55 |
| SP | Scherzer, M.Scherzer, Max # >> | 37 | 2021 | R | 100 | 5 | 5 | 2 | 3 | 5.10 | .328 | 1.47 | 9.3 | 3.9 | 6.3 | 30.0 | 31 | 19 | 17 | 6 | 13 | 21 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 5.50 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 82 | 5 | 5 | 3 | 1 | 3.08 | .317 | 1.39 | 8.8 | 3.8 | 4.5 | 38.0 | 37 | 13 | 13 | 4 | 16 | 19 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 4.63 |
| SP | Strasburg, S.Strasburg, Stephen >> | 24 | 2013 | R | 64 | 5 | 5 | 3 | 1 | 5.00 | .357 | 1.63 | 10.7 | 4.0 | 6.7 | 27.0 | 32 | 16 | 15 | 1 | 12 | 20 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 3.44 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 12 | 0 | 2 | 1 | 3.46 | .371 | 1.77 | 14.5 | 1.4 | 9.0 | 13.0 | 21 | 5 | 5 | 2 | 2 | 13 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.46 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 89 | 12 | 0 | 1 | 0 | 0.34 | .092 | 0.30 | 1.7 | 1.0 | 6.2 | 26.1 | 5 | 1 | 1 | 1 | 3 | 18 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.46 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 82 | 9 | 0 | 1 | 1 | 2.38 | .209 | 0.79 | 5.7 | 1.6 | 7.4 | 11.1 | 7 | 3 | 3 | 1 | 2 | 9 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.09 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 76 | 5 | 0 | 1 | 0 | 1.69 | .273 | 1.13 | 10.8 | 0.0 | 5.4 | 5.1 | 6 | 1 | 1 | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.80 |
| RP | Hudson, D.Hudson, Daniel >> | 34 | 2021 | R | 72 | 2 | 0 | 0 | 0 | 0.00 | .333 | 1.50 | 13.5 | 4.5 | 4.5 | 2.2 | 3 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| RP | McGowin, K.McGowin, Kyle >> | 29 | 2021 | R | 44 | 5 | 0 | 0 | 0 | 1.80 | .375 | 1.80 | 7.2 | 9.0 | 9.0 | 5.0 | 4 | 1 | 1 | 0 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Weems, J.Weems, Jordan >> | 29 | 2022 | R | 30 | 5 | 0 | 0 | 0 | 1.08 | .265 | 1.08 | 6.8 | 3.4 | 10.1 | 8.1 | 6 | 1 | 1 | 0 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.88 |
| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 97 | 6 | 0 | 3 | 2 | 6.00 | .331 | 1.42 | 9.3 | 3.5 | 9.3 | 33.0 | 34 | 22 | 22 | 7 | 13 | 34 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 5.06 |