| SP | Maddux, G.Maddux, Greg >> | 22 | 1988 | R | 37 | 10 | 10 | 0 | 5 | 4.93 | .350 | 1.59 | 9.5 | 4.8 | 3.3 | 69.1 | 73 | 42 | 38 | 2 | 37 | 25 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 4.35 |
| SP | Sutcliffe, R.Sutcliffe, Rick # >> | 28 | 1984 | R | 58 | 10 | 10 | 3 | 6 | 5.46 | .344 | 1.54 | 11.0 | 3.0 | 8.9 | 64.1 | 78 | 40 | 39 | 12 | 21 | 63 | 2 | 0 | 0 | 1 | 3 | 2 | 2 | 4.55 |
| SP | Zambrano, C.Zambrano, Carlos >> | 23 | 2004 | R | 45 | 7 | 7 | 2 | 4 | 4.27 | .298 | 1.25 | 7.3 | 4.2 | 7.1 | 52.2 | 42 | 25 | 25 | 5 | 24 | 41 | 1 | 0 | 0 | 0 | 3 | 1 | 0 | 4.12 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 55 | 9 | 9 | 3 | 3 | 5.28 | .358 | 1.63 | 10.2 | 4.5 | 5.3 | 46.0 | 52 | 27 | 27 | 5 | 23 | 27 | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 4.87 |
| SP | Jenkins, F.Jenkins, Fergie >> | 41 | 1983 | R | 21 | 9 | 9 | 1 | 8 | 6.85 | .366 | 1.68 | 11.3 | 4.0 | 4.8 | 43.1 | 54 | 35 | 33 | 6 | 19 | 23 | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 5.21 |
| RP | Sutter, B.Sutter, Bruce >> | 25 | 1978 | R | 30 | 27 | 0 | 1 | 2 | 2.72 | .273 | 1.13 | 7.5 | 2.8 | 8.8 | 36.1 | 30 | 14 | 11 | 1 | 11 | 35 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2.33 |
| RP | Wendell, T.Wendell, Turk >> | 30 | 1997 | R | 13 | 18 | 0 | 1 | 2 | 3.55 | .303 | 1.26 | 9.0 | 2.5 | 5.0 | 25.1 | 25 | 13 | 10 | 0 | 7 | 14 | 0 | 0 | 3 | 0 | 0 | 1 | 2 | 2.84 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 28 | 2004 | R | 15 | 10 | 0 | 0 | 1 | 2.31 | .314 | 1.37 | 8.2 | 4.9 | 8.2 | 11.2 | 10 | 3 | 3 | 1 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Samardzija, J.Samardzija, Jeff >> | 26 | 2011 | R | 29 | 12 | 0 | 1 | 1 | 6.14 | .323 | 1.43 | 8.4 | 5.1 | 7.7 | 14.2 | 13 | 10 | 10 | 0 | 8 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.00 |