| SP | Bender, C.Bender, Chief † >> | 26 | 1910 | R | 85 | 33 | 33 | 21 | 9 | 4.06 | .296 | 1.24 | 8.4 | 2.8 | 5.6 | 268.1 | 250 | 136 | 121 | 30 | 83 | 168 | 14 | 0 | 0 | 3 | 19 | 5 | 8 | 4.19 |
| SP | Fingers, R.Fingers, Rollie # >> | 25 | 1971 | R | 80 | 32 | 32 | 0 | 5 | 4.47 | .298 | 1.25 | 9.1 | 2.2 | 5.9 | 102.2 | 103 | 55 | 51 | 14 | 25 | 67 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 4.29 |
| SP | Samardzija, J.Samardzija, Jeff # >> | 29 | 2014 | R | 79 | 32 | 32 | 15 | 6 | 4.90 | .311 | 1.32 | 10.0 | 1.9 | 5.3 | 233.1 | 259 | 140 | 127 | 34 | 49 | 136 | 5 | 0 | 0 | 3 | 11 | 8 | 5 | 4.46 |
| RP | Doolittle, S.Doolittle, Sean >> | 27 | 2014 | L | 91 | 87 | 0 | 24 | 2 | 4.08 | .289 | 1.19 | 8.4 | 2.4 | 9.1 | 114.2 | 106 | 52 | 52 | 11 | 31 | 115 | 0 | 0 | 4 | 0 | 0 | 3 | 0 | 3.13 |
| RP | Madson, R.Madson, Ryan >> | 37 | 2017 | R | 74 | 85 | 0 | 16 | 6 | 2.97 | .268 | 1.09 | 7.7 | 2.1 | 8.8 | 118.1 | 101 | 42 | 39 | 12 | 28 | 115 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 3.11 |
| CL | Eckersley, D.Eckersley, Dennis † >> | 35 | 1989 | R | 94 | 76 | 0 | 5 | 5 | 2.71 | .268 | 1.07 | 8.3 | 1.3 | 7.5 | 83.0 | 77 | 27 | 25 | 8 | 12 | 69 | 0 | 39 | 9 | 0 | 0 | 2 | 0 | 3.10 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 84 | 75 | 0 | 13 | 2 | 3.11 | .276 | 1.12 | 7.0 | 3.1 | 7.7 | 110.0 | 85 | 39 | 38 | 14 | 38 | 94 | 0 | 3 | 3 | 0 | 0 | 3 | 0 | 4.06 |
| RP | Wendelken, J.Wendelken, J.B. >> | 26 | 2019 | R | 63 | 81 | 0 | 14 | 2 | 3.89 | .274 | 1.09 | 6.6 | 3.2 | 9.3 | 113.1 | 83 | 52 | 49 | 11 | 40 | 117 | 0 | 1 | 5 | 0 | 0 | 5 | 3 | 3.39 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 61 | 73 | 0 | 3 | 3 | 3.47 | .303 | 1.29 | 8.9 | 2.7 | 8.8 | 83.0 | 82 | 34 | 32 | 10 | 25 | 81 | 0 | 2 | 6 | 0 | 0 | 1 | 0 | 3.55 |
| RP | Miller, M.Miller, Mason >> | 26 | 2025 | R | 69 | 56 | 0 | 2 | 0 | 3.09 | .294 | 1.23 | 6.2 | 4.9 | 9.0 | 64.0 | 44 | 22 | 22 | 7 | 35 | 64 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 4.11 |