| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 85 | 7 | 7 | 5 | 1 | 2.44 | .259 | 1.02 | 6.7 | 2.4 | 6.3 | 59.0 | 44 | 23 | 16 | 8 | 16 | 41 | 5 | 0 | 0 | 0 | 5 | 2 | 1 | 4.29 |
| SP | Fingers, R.Fingers, Rollie >> | 25 | 1971 | R | 80 | 7 | 7 | 0 | 0 | 6.14 | .340 | 1.55 | 11.5 | 2.5 | 4.9 | 22.0 | 28 | 15 | 15 | 5 | 6 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.68 |
| SP | Samardzija, J.Samardzija, Jeff # >> | 29 | 2014 | R | 79 | 6 | 6 | 2 | 2 | 4.70 | .315 | 1.33 | 10.7 | 1.4 | 5.4 | 38.1 | 45 | 23 | 20 | 4 | 6 | 23 | 1 | 0 | 0 | 1 | 1 | 2 | 0 | 3.79 |
| SP | Soria, J.Soria, Joakim >> | 35 | 2019 | R | 72 | 8 | 6 | 1 | 0 | 6.30 | .388 | 1.90 | 9.9 | 7.2 | 6.3 | 10.0 | 11 | 7 | 7 | 1 | 8 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.30 |
| RP | Doolittle, S.Doolittle, Sean >> | 27 | 2014 | L | 91 | 17 | 0 | 3 | 1 | 4.63 | .300 | 1.20 | 8.6 | 2.3 | 7.4 | 23.1 | 22 | 12 | 12 | 1 | 6 | 19 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 2.96 |
| RP | Madson, R.Madson, Ryan >> | 37 | 2017 | R | 74 | 18 | 0 | 0 | 1 | 2.25 | .258 | 1.00 | 6.8 | 2.3 | 9.0 | 24.0 | 18 | 9 | 6 | 2 | 6 | 24 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 2.96 |
| CL | Eckersley, D.Eckersley, Dennis >> | 35 | 1989 | R | 94 | 16 | 0 | 1 | 2 | 3.63 | .278 | 1.15 | 8.5 | 2.1 | 11.1 | 17.1 | 16 | 7 | 7 | 1 | 4 | 21 | 0 | 7 | 2 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 84 | 16 | 0 | 4 | 1 | 3.18 | .277 | 1.15 | 7.0 | 3.7 | 6.1 | 22.2 | 17 | 8 | 8 | 3 | 9 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.64 |
| RP | Wendelken, J.Wendelken, J.B. >> | 26 | 2019 | R | 63 | 16 | 0 | 4 | 0 | 2.19 | .229 | 0.85 | 5.3 | 2.6 | 6.8 | 24.2 | 14 | 6 | 6 | 2 | 7 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.58 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 61 | 18 | 0 | 1 | 2 | 7.02 | .405 | 1.98 | 14.1 | 4.5 | 9.0 | 16.2 | 25 | 13 | 13 | 3 | 8 | 16 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 5.13 |
| RP | Miller, M.Miller, Mason >> | 26 | 2025 | R | 69 | 12 | 0 | 0 | 0 | 2.45 | .241 | 0.95 | 3.9 | 5.1 | 9.6 | 14.2 | 6 | 4 | 4 | 2 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.43 |