| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 97 | 10 | 10 | 5 | 4 | 4.68 | .300 | 1.28 | 8.4 | 3.3 | 8.5 | 57.2 | 53 | 31 | 30 | 11 | 21 | 54 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 4.72 |
| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 90 | 9 | 9 | 3 | 4 | 4.92 | .329 | 1.45 | 8.6 | 4.5 | 7.6 | 64.0 | 61 | 37 | 35 | 5 | 32 | 54 | 3 | 0 | 0 | 2 | 3 | 1 | 1 | 3.88 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 74 | 9 | 9 | 6 | 2 | 3.64 | .303 | 1.29 | 8.3 | 3.4 | 4.5 | 64.1 | 59 | 26 | 26 | 7 | 24 | 32 | 1 | 0 | 0 | 0 | 7 | 1 | 2 | 4.59 |
| SP | Strasburg, S.Strasburg, Stephen >> | 24 | 2013 | R | 66 | 9 | 9 | 4 | 3 | 5.33 | .324 | 1.44 | 9.4 | 3.8 | 8.1 | 50.2 | 52 | 30 | 30 | 8 | 21 | 45 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 4.54 |
| SP | Martinez, D.Martinez, Dennis # >> | 37 | 1992 | R | 63 | 9 | 9 | 6 | 1 | 3.97 | .274 | 1.10 | 7.4 | 2.5 | 4.9 | 68.0 | 56 | 32 | 30 | 4 | 19 | 37 | 3 | 0 | 0 | 1 | 4 | 2 | 2 | 3.60 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 19 | 0 | 0 | 0 | 3.65 | .321 | 1.42 | 10.9 | 2.3 | 9.4 | 24.2 | 29 | 12 | 10 | 3 | 6 | 25 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.29 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 92 | 16 | 0 | 1 | 1 | 2.70 | .254 | 0.96 | 7.3 | 1.7 | 11.3 | 16.2 | 13 | 5 | 5 | 1 | 3 | 20 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 2.06 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 78 | 9 | 0 | 1 | 1 | 3.72 | .326 | 1.45 | 14.0 | 0.0 | 11.0 | 9.2 | 14 | 4 | 4 | 0 | 0 | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0.56 |
| RP | Hudson, D.Hudson, Daniel >> | 34 | 2021 | R | 70 | 4 | 0 | 0 | 0 | 9.00 | .400 | 2.00 | 11.3 | 6.8 | 9.0 | 4.0 | 5 | 4 | 4 | 2 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.75 |
| RP | Valdez, S.Valdez, Sergio >> | 28 | 1992 | R | 59 | 14 | 0 | 2 | 0 | 2.89 | .349 | 1.61 | 13.0 | 2.0 | 5.0 | 9.1 | 13 | 3 | 3 | 1 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Youmans, F.Youmans, Floyd >> | 22 | 1986 | R | 61 | 4 | 0 | 2 | 0 | 2.38 | .333 | 1.50 | 7.0 | 7.0 | 7.4 | 22.2 | 17 | 6 | 6 | 2 | 17 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.86 |