| SP | Strasburg, S.Strasburg, Stephen # >> | 28 | 2017 | R | 75 | 36 | 36 | 12 | 13 | 4.79 | .308 | 1.32 | 8.7 | 3.3 | 8.9 | 176.2 | 170 | 97 | 94 | 16 | 64 | 175 | 1 | 0 | 0 | 1 | 12 | 2 | 2 | 3.32 |
| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 95 | 36 | 36 | 12 | 14 | 5.03 | .316 | 1.37 | 8.7 | 3.7 | 8.2 | 211.0 | 203 | 123 | 118 | 26 | 86 | 192 | 6 | 0 | 0 | 2 | 15 | 3 | 1 | 4.05 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 84 | 36 | 34 | 16 | 9 | 4.53 | .325 | 1.41 | 9.2 | 3.6 | 5.2 | 204.2 | 208 | 110 | 103 | 20 | 81 | 117 | 2 | 0 | 0 | 0 | 18 | 6 | 4 | 4.41 |
| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 97 | 31 | 31 | 13 | 6 | 3.98 | .297 | 1.25 | 8.2 | 3.2 | 8.9 | 162.2 | 147 | 72 | 72 | 24 | 57 | 161 | 1 | 0 | 0 | 1 | 11 | 2 | 0 | 4.03 |
| SP | Martinez, D.Martinez, Dennis >> | 37 | 1992 | R | 70 | 35 | 31 | 13 | 10 | 4.73 | .326 | 1.43 | 9.4 | 3.4 | 4.4 | 196.0 | 205 | 105 | 103 | 23 | 75 | 95 | 1 | 1 | 1 | 0 | 15 | 4 | 3 | 4.77 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 100 | 113 | 0 | 5 | 2 | 4.05 | .309 | 1.34 | 8.8 | 3.3 | 9.6 | 97.2 | 95 | 46 | 44 | 9 | 36 | 103 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 3.20 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 89 | 69 | 0 | 3 | 3 | 2.33 | .271 | 1.08 | 6.9 | 2.8 | 5.3 | 112.0 | 86 | 30 | 29 | 10 | 35 | 66 | 0 | 3 | 3 | 0 | 0 | 4 | 0 | 4.03 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 80 | 73 | 0 | 8 | 4 | 3.01 | .273 | 1.12 | 7.3 | 2.8 | 8.6 | 95.2 | 77 | 35 | 32 | 10 | 30 | 91 | 0 | 4 | 4 | 0 | 0 | 1 | 0 | 3.43 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 78 | 83 | 0 | 8 | 4 | 3.26 | .284 | 1.17 | 6.7 | 3.8 | 8.7 | 99.1 | 74 | 38 | 36 | 8 | 42 | 96 | 0 | 13 | 2 | 0 | 0 | 2 | 3 | 3.44 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 75 | 84 | 0 | 3 | 3 | 4.11 | .287 | 1.20 | 7.0 | 3.8 | 9.3 | 105.0 | 82 | 48 | 48 | 18 | 44 | 108 | 0 | 6 | 8 | 0 | 0 | 1 | 0 | 4.46 |
| RP | Hudson, D.Hudson, Daniel >> | 34 | 2021 | R | 62 | 60 | 0 | 2 | 5 | 5.29 | .326 | 1.44 | 9.3 | 3.8 | 11.3 | 64.2 | 66 | 39 | 38 | 9 | 27 | 80 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 3.64 |