| SP | Scherzer, M.Scherzer, Max >> | 39 | 2023 | R | 91 | 35 | 35 | 0 | 6 | 4.61 | .333 | 1.49 | 8.8 | 4.6 | 8.4 | 107.1 | 105 | 59 | 55 | 17 | 55 | 100 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 4.77 |
| SP | deGrom, J.deGrom, Jacob >> | 35 | 2023 | R | 100 | 36 | 36 | 2 | 8 | 5.15 | .326 | 1.44 | 10.0 | 3.1 | 8.5 | 106.2 | 118 | 61 | 61 | 12 | 36 | 100 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.63 |
| SP | Ogando, A.Ogando, Alexi >> | 28 | 2012 | R | 78 | 65 | 31 | 0 | 3 | 5.81 | .325 | 1.43 | 8.9 | 4.1 | 9.2 | 83.2 | 82 | 54 | 54 | 16 | 38 | 85 | 0 | 1 | 1 | 0 | 0 | 1 | 5 | 4.87 |
| SP | Duckworth, J.Duckworth, Jim >> | 26 | 1965 | R | 55 | 74 | 26 | 3 | 6 | 6.65 | .371 | 1.77 | 9.1 | 6.9 | 8.1 | 89.1 | 90 | 66 | 66 | 14 | 68 | 80 | 0 | 5 | 1 | 0 | 0 | 0 | 6 | 5.54 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 100 | 108 | 0 | 13 | 10 | 3.16 | .304 | 1.29 | 7.4 | 4.2 | 9.5 | 162.1 | 134 | 63 | 57 | 16 | 75 | 171 | 0 | 6 | 7 | 0 | 0 | 4 | 0 | 3.64 |
| RP | Leclerc, J.Leclerc, Jose # >> | 24 | 2018 | R | 88 | 105 | 0 | 12 | 4 | 3.72 | .280 | 1.16 | 6.5 | 4.0 | 9.8 | 135.1 | 97 | 59 | 56 | 6 | 60 | 147 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 2.76 |
| RP | Armstrong, S.Armstrong, Shawn >> | 34 | 2025 | R | 86 | 107 | 0 | 14 | 4 | 4.77 | .303 | 1.30 | 7.8 | 3.9 | 8.1 | 132.0 | 114 | 75 | 70 | 21 | 57 | 119 | 0 | 5 | 4 | 0 | 0 | 1 | 3 | 4.58 |
| RP | Uehara, K.Uehara, Koji # >> | 37 | 2012 | R | 96 | 97 | 0 | 10 | 2 | 4.58 | .340 | 1.53 | 10.9 | 2.8 | 10.0 | 118.0 | 143 | 65 | 60 | 18 | 37 | 131 | 0 | 1 | 7 | 0 | 0 | 2 | 4 | 3.75 |
| RP | Kirkman, M.Kirkman, Michael >> | 25 | 2012 | L | 35 | 101 | 0 | 7 | 5 | 5.61 | .337 | 1.48 | 8.1 | 5.4 | 7.6 | 126.2 | 113 | 87 | 79 | 18 | 75 | 107 | 0 | 1 | 2 | 0 | 0 | 5 | 4 | 5.06 |
| RP | Yates, K.Yates, Kirby † >> | 37 | 2024 | R | 93 | 103 | 0 | 11 | 6 | 5.57 | .356 | 1.63 | 7.9 | 6.8 | 10.0 | 118.0 | 103 | 74 | 73 | 17 | 89 | 131 | 0 | 8 | 5 | 0 | 0 | 4 | 3 | 5.02 |