| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 71 | 20 | 20 | 7 | 10 | 4.21 | .309 | 1.31 | 8.3 | 3.6 | 8.4 | 113.1 | 104 | 55 | 53 | 15 | 45 | 105 | 0 | 0 | 0 | 0 | 10 | 3 | 2 | 4.14 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 70 | 19 | 19 | 5 | 9 | 4.92 | .319 | 1.38 | 9.2 | 3.2 | 8.4 | 109.2 | 112 | 60 | 60 | 17 | 39 | 102 | 1 | 0 | 0 | 1 | 9 | 3 | 2 | 4.31 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 69 | 18 | 18 | 7 | 5 | 2.68 | .266 | 1.07 | 7.1 | 2.5 | 9.2 | 114.1 | 90 | 36 | 34 | 7 | 32 | 116 | 0 | 0 | 0 | 0 | 11 | 2 | 4 | 2.66 |
| SP | Paddack, C.Paddack, Chris † # >> | 23 | 2019 | R | 63 | 18 | 18 | 10 | 2 | 3.74 | .279 | 1.14 | 8.5 | 1.8 | 8.0 | 101.0 | 95 | 43 | 42 | 14 | 20 | 90 | 0 | 0 | 0 | 0 | 8 | 2 | 0 | 3.67 |
| SP | Luebke, C.Luebke, Cory >> | 26 | 2011 | L | 59 | 17 | 17 | 0 | 0 | 4.14 | .307 | 1.28 | 7.8 | 3.9 | 7.6 | 58.2 | 50 | 27 | 27 | 4 | 25 | 49 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3.66 |
| SP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 99 | 17 | 1 | 4 | 0 | 3.68 | .281 | 1.17 | 7.5 | 3.3 | 9.8 | 36.2 | 30 | 15 | 15 | 3 | 13 | 39 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 3.00 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 97 | 49 | 0 | 5 | 2 | 4.29 | .287 | 1.21 | 6.7 | 4.1 | 10.4 | 63.0 | 47 | 33 | 30 | 10 | 29 | 73 | 0 | 6 | 2 | 0 | 0 | 0 | 1 | 4.13 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 93 | 41 | 0 | 2 | 0 | 3.19 | .298 | 1.23 | 6.0 | 5.1 | 7.7 | 48.0 | 32 | 19 | 17 | 2 | 27 | 41 | 0 | 5 | 3 | 0 | 0 | 2 | 5 | 3.65 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 74 | 27 | 0 | 3 | 3 | 2.82 | .223 | 0.86 | 4.7 | 3.1 | 9.9 | 38.1 | 20 | 12 | 12 | 3 | 13 | 42 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 2.84 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 68 | 33 | 0 | 2 | 4 | 4.38 | .316 | 1.33 | 9.9 | 2.1 | 6.9 | 39.0 | 43 | 19 | 19 | 7 | 9 | 30 | 0 | 4 | 3 | 0 | 0 | 2 | 0 | 4.64 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 65 | 27 | 0 | 3 | 2 | 3.10 | .298 | 1.21 | 7.1 | 3.7 | 9.3 | 29.0 | 23 | 10 | 10 | 2 | 12 | 30 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 3.28 |
| RP | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 61 | 24 | 0 | 0 | 3 | 1.53 | .241 | 0.92 | 5.9 | 2.5 | 9.0 | 29.1 | 19 | 5 | 5 | 1 | 8 | 29 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 2.38 |