| SP | Martinez, P.Martinez, Pedro † # >> | 29 | 2000 | R | 100 | 38 | 38 | 20 | 12 | 3.19 | .267 | 1.06 | 7.3 | 2.3 | 9.5 | 287.2 | 232 | 105 | 102 | 31 | 74 | 304 | 13 | 0 | 0 | 3 | 27 | 9 | 3 | 3.15 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 36 | 36 | 20 | 11 | 4.22 | .279 | 1.13 | 8.0 | 2.2 | 8.1 | 249.1 | 221 | 118 | 117 | 30 | 61 | 225 | 7 | 0 | 0 | 2 | 17 | 7 | 6 | 3.58 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 32 | 31 | 10 | 13 | 5.04 | .310 | 1.32 | 9.0 | 2.9 | 4.6 | 198.1 | 197 | 115 | 111 | 36 | 64 | 101 | 3 | 0 | 0 | 1 | 11 | 6 | 2 | 5.40 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 92 | 0 | 6 | 2 | 2.02 | .271 | 1.07 | 4.6 | 5.0 | 10.2 | 111.1 | 57 | 26 | 25 | 3 | 62 | 126 | 0 | 18 | 2 | 0 | 0 | 5 | 7 | 2.89 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 70 | 0 | 4 | 6 | 3.56 | .298 | 1.25 | 8.3 | 2.9 | 7.6 | 81.0 | 75 | 33 | 32 | 10 | 26 | 68 | 0 | 12 | 2 | 0 | 0 | 2 | 0 | 3.96 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 38 | 0 | 3 | 0 | 2.12 | .218 | 0.84 | 4.1 | 3.5 | 7.8 | 46.2 | 21 | 11 | 11 | 2 | 18 | 40 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 30 | 0 | 3 | 1 | 3.90 | .349 | 1.61 | 10.7 | 3.9 | 10.7 | 32.1 | 38 | 14 | 14 | 5 | 14 | 38 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.97 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 14 | 0 | 1 | 3 | 9.33 | .368 | 1.69 | 11.0 | 4.5 | 6.0 | 18.1 | 22 | 19 | 19 | 5 | 9 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.94 |