| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 33 | 33 | 16 | 12 | 3.87 | .312 | 1.34 | 10.3 | 1.8 | 8.3 | 235.0 | 269 | 107 | 101 | 26 | 46 | 216 | 6 | 0 | 0 | 2 | 22 | 5 | 5 | 3.25 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 33 | 33 | 12 | 16 | 4.58 | .324 | 1.40 | 9.4 | 3.2 | 8.1 | 220.0 | 229 | 122 | 112 | 27 | 78 | 197 | 3 | 0 | 0 | 2 | 15 | 9 | 4 | 3.99 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 79 | 32 | 32 | 11 | 12 | 5.25 | .319 | 1.40 | 9.6 | 3.0 | 5.4 | 214.1 | 228 | 126 | 125 | 35 | 72 | 129 | 9 | 0 | 0 | 1 | 12 | 1 | 6 | 4.94 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 32 | 32 | 14 | 11 | 4.72 | .312 | 1.33 | 9.2 | 2.9 | 4.5 | 221.0 | 225 | 122 | 116 | 24 | 70 | 110 | 6 | 0 | 0 | 2 | 14 | 6 | 1 | 4.45 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 32 | 31 | 12 | 14 | 5.09 | .334 | 1.47 | 9.8 | 3.5 | 5.7 | 205.0 | 223 | 118 | 116 | 20 | 79 | 130 | 4 | 0 | 0 | 0 | 15 | 6 | 6 | 4.24 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 100 | 0 | 6 | 5 | 3.60 | .291 | 1.21 | 8.0 | 3.0 | 8.7 | 122.2 | 108 | 54 | 49 | 14 | 40 | 118 | 0 | 15 | 4 | 0 | 0 | 3 | 8 | 3.61 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 34 | 0 | 0 | 3 | 3.96 | .293 | 1.24 | 6.6 | 4.7 | 10.4 | 38.2 | 28 | 17 | 17 | 5 | 20 | 44 | 0 | 2 | 0 | 0 | 0 | 0 | 4 | 3.97 |