| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 32 | 32 | 15 | 8 | 4.18 | .300 | 1.27 | 8.5 | 2.9 | 7.3 | 211.0 | 200 | 99 | 98 | 24 | 68 | 172 | 3 | 0 | 0 | 1 | 17 | 3 | 3 | 3.86 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 32 | 18 | 10 | 9 | 4.82 | .331 | 1.46 | 8.1 | 5.1 | 7.6 | 132.2 | 119 | 75 | 71 | 17 | 75 | 111 | 0 | 2 | 2 | 0 | 12 | 3 | 3 | 4.77 |
| RP | Miller, A.Miller, Andrew # >> | 29 | 2014 | L | 88 | 99 | 0 | 8 | 1 | 3.40 | .266 | 1.09 | 7.1 | 2.7 | 7.8 | 87.1 | 69 | 33 | 33 | 13 | 26 | 75 | 0 | 2 | 4 | 0 | 0 | 0 | 4 | 4.11 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 87 | 0 | 9 | 3 | 3.70 | .306 | 1.30 | 7.7 | 4.1 | 8.6 | 97.1 | 83 | 42 | 40 | 6 | 44 | 93 | 0 | 4 | 3 | 0 | 0 | 2 | 2 | 3.31 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 73 | 0 | 3 | 6 | 3.99 | .307 | 1.30 | 7.7 | 4.1 | 6.2 | 76.2 | 65 | 34 | 34 | 10 | 35 | 52 | 0 | 4 | 3 | 0 | 0 | 2 | 1 | 4.80 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 68 | 0 | 2 | 8 | 2.89 | .270 | 1.10 | 5.8 | 4.1 | 9.2 | 74.2 | 48 | 25 | 24 | 7 | 34 | 76 | 0 | 31 | 8 | 0 | 0 | 1 | 3 | 3.59 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 46 | 0 | 3 | 3 | 3.08 | .279 | 1.16 | 8.1 | 2.4 | 8.1 | 52.2 | 47 | 20 | 18 | 9 | 14 | 47 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.25 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 6 | 0 | 0 | 0 | 2.74 | .281 | 1.17 | 5.5 | 5.1 | 3.5 | 23.0 | 14 | 7 | 7 | 2 | 13 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.04 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 74 | 23 | 14 | 6 | 7 | 4.87 | .304 | 1.28 | 8.8 | 2.8 | 4.2 | 109.0 | 106 | 59 | 59 | 15 | 34 | 51 | 2 | 1 | 0 | 0 | 5 | 3 | 0 | 4.87 |