| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 33 | 33 | 16 | 12 | 3.47 | .279 | 1.13 | 7.6 | 2.6 | 8.8 | 230.2 | 194 | 90 | 89 | 23 | 67 | 226 | 10 | 0 | 0 | 2 | 21 | 7 | 3 | 3.30 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 32 | 32 | 15 | 10 | 4.05 | .283 | 1.16 | 7.8 | 2.7 | 5.4 | 226.2 | 196 | 105 | 102 | 23 | 67 | 135 | 5 | 0 | 0 | 3 | 17 | 5 | 3 | 4.08 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 32 | 32 | 15 | 11 | 4.62 | .299 | 1.27 | 9.0 | 2.4 | 8.1 | 210.1 | 211 | 109 | 108 | 31 | 56 | 189 | 3 | 0 | 0 | 2 | 16 | 2 | 5 | 3.95 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 22 | 21 | 10 | 8 | 4.08 | .298 | 1.27 | 8.2 | 3.2 | 6.2 | 154.1 | 141 | 71 | 70 | 9 | 55 | 106 | 6 | 0 | 0 | 0 | 12 | 1 | 5 | 3.47 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 56 | 0 | 2 | 7 | 4.74 | .290 | 1.21 | 8.2 | 2.7 | 8.4 | 57.0 | 52 | 31 | 30 | 8 | 17 | 53 | 0 | 34 | 2 | 0 | 0 | 1 | 1 | 3.91 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 38 | 0 | 0 | 2 | 2.89 | .200 | 0.72 | 4.4 | 2.2 | 7.5 | 37.1 | 18 | 12 | 12 | 2 | 9 | 31 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 2.84 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 71 | 0 | 10 | 2 | 3.69 | .303 | 1.27 | 9.8 | 1.7 | 6.0 | 68.1 | 74 | 31 | 28 | 6 | 13 | 45 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 3.49 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 36 | 0 | 5 | 1 | 2.35 | .238 | 0.94 | 4.7 | 3.8 | 8.1 | 38.1 | 20 | 10 | 10 | 5 | 16 | 34 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.18 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 21 | 0 | 1 | 0 | 7.07 | .344 | 1.50 | 10.3 | 3.2 | 4.5 | 14.0 | 16 | 11 | 11 | 3 | 5 | 7 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 6.07 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 15 | 0 | 0 | 0 | 3.60 | .231 | 0.90 | 6.3 | 1.8 | 6.3 | 20.0 | 14 | 8 | 8 | 1 | 4 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.85 |