| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 33 | 33 | 14 | 13 | 3.57 | .270 | 1.08 | 7.3 | 2.4 | 8.9 | 219.1 | 178 | 95 | 87 | 31 | 59 | 217 | 2 | 0 | 0 | 0 | 21 | 6 | 0 | 3.75 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 32 | 32 | 13 | 10 | 3.89 | .286 | 1.17 | 8.5 | 2.0 | 4.8 | 215.1 | 204 | 109 | 93 | 15 | 47 | 114 | 6 | 0 | 0 | 2 | 18 | 8 | 8 | 3.61 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 32 | 32 | 10 | 13 | 4.77 | .318 | 1.40 | 9.6 | 3.0 | 5.4 | 164.0 | 175 | 93 | 87 | 25 | 54 | 98 | 0 | 0 | 0 | 0 | 8 | 0 | 5 | 4.77 |
| CL | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 74 | 0 | 1 | 5 | 5.13 | .319 | 1.41 | 10.0 | 2.6 | 9.2 | 79.0 | 88 | 46 | 45 | 12 | 23 | 81 | 0 | 34 | 6 | 0 | 0 | 0 | 2 | 3.80 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 69 | 0 | 6 | 1 | 3.95 | .309 | 1.33 | 6.8 | 5.2 | 7.7 | 86.2 | 65 | 43 | 38 | 12 | 50 | 74 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 4.87 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 53 | 0 | 5 | 1 | 5.10 | .319 | 1.39 | 9.5 | 3.0 | 8.5 | 67.0 | 71 | 46 | 38 | 13 | 22 | 63 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 4.67 |