| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 34 | 34 | 10 | 17 | 4.24 | .316 | 1.35 | 8.0 | 4.1 | 9.2 | 204.0 | 182 | 100 | 96 | 24 | 94 | 208 | 0 | 0 | 0 | 0 | 17 | 7 | 4 | 3.98 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 33 | 33 | 16 | 9 | 4.17 | .288 | 1.20 | 8.5 | 2.3 | 6.9 | 207.1 | 196 | 100 | 96 | 28 | 52 | 159 | 1 | 0 | 0 | 0 | 15 | 4 | 2 | 4.03 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 55 | 32 | 32 | 7 | 17 | 6.62 | .365 | 1.69 | 11.8 | 3.4 | 6.1 | 170.0 | 223 | 131 | 125 | 43 | 64 | 115 | 0 | 0 | 0 | 0 | 9 | 6 | 3 | 6.17 |
| SP | Leiter, A.Leiter, Al # >> | 35 | 2000 | L | 41 | 33 | 32 | 9 | 11 | 5.42 | .341 | 1.51 | 10.2 | 3.5 | 8.1 | 202.2 | 228 | 125 | 122 | 31 | 78 | 182 | 0 | 0 | 0 | 0 | 12 | 8 | 4 | 4.47 |
| SP | Mulder, M.Mulder, Mark >> | 24 | 2001 | L | 29 | 33 | 31 | 8 | 16 | 6.09 | .368 | 1.69 | 11.1 | 4.1 | 7.0 | 186.1 | 230 | 128 | 126 | 28 | 85 | 144 | 2 | 0 | 1 | 0 | 9 | 10 | 7 | 4.94 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 101 | 0 | 5 | 6 | 4.46 | .303 | 1.28 | 8.1 | 3.4 | 10.1 | 143.1 | 129 | 71 | 71 | 19 | 54 | 161 | 0 | 10 | 3 | 0 | 0 | 4 | 0 | 3.69 |
| RP | Smoltz, J.Smoltz, John # >> | 36 | 2003 | R | 75 | 86 | 0 | 7 | 5 | 4.73 | .333 | 1.43 | 10.2 | 2.8 | 9.2 | 106.2 | 120 | 56 | 56 | 12 | 33 | 108 | 0 | 6 | 3 | 0 | 0 | 7 | 6 | 3.57 |
| RP | Takatsu, S.Takatsu, Shingo >> | 36 | 2004 | R | 56 | 73 | 0 | 8 | 2 | 3.21 | .310 | 1.33 | 8.2 | 3.8 | 6.2 | 89.2 | 81 | 34 | 32 | 11 | 38 | 61 | 0 | 8 | 3 | 0 | 0 | 2 | 0 | 4.58 |
| RP | Urbina, U.Urbina, Ugueth >> | 28 | 2002 | R | 42 | 55 | 0 | 2 | 2 | 7.73 | .364 | 1.69 | 10.1 | 5.1 | 10.7 | 64.0 | 72 | 55 | 55 | 16 | 36 | 76 | 0 | 6 | 2 | 0 | 0 | 2 | 4 | 5.66 |
| RP | Shields, S.Shields, Scot >> | 30 | 2005 | R | 30 | 52 | 0 | 1 | 4 | 3.95 | .324 | 1.41 | 8.9 | 3.8 | 9.1 | 66.0 | 65 | 29 | 29 | 10 | 28 | 67 | 0 | 3 | 3 | 0 | 0 | 2 | 4 | 4.30 |