| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 8 | 8 | 1 | 2 | 1.99 | .278 | 1.16 | 7.2 | 3.4 | 8.3 | 40.2 | 32 | 9 | 9 | 4 | 15 | 37 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 3.58 |
| SP | Sabathia, C.Sabathia, CC # >> | 28 | 2008 | L | 60 | 7 | 7 | 1 | 4 | 6.70 | .344 | 1.57 | 9.4 | 4.8 | 8.6 | 47.0 | 49 | 35 | 35 | 8 | 25 | 45 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 4.89 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 58 | 7 | 7 | 2 | 3 | 3.91 | .284 | 1.17 | 8.3 | 2.2 | 7.5 | 53.0 | 49 | 23 | 23 | 9 | 13 | 44 | 1 | 0 | 0 | 0 | 4 | 1 | 0 | 4.34 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 48 | 7 | 7 | 2 | 2 | 4.22 | .329 | 1.43 | 10.3 | 2.6 | 5.7 | 49.0 | 56 | 23 | 23 | 5 | 14 | 31 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 4.04 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 20 | 0 | 3 | 1 | 1.44 | .260 | 1.02 | 6.7 | 2.6 | 10.5 | 31.1 | 23 | 6 | 5 | 2 | 9 | 36 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.48 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 80 | 15 | 0 | 0 | 0 | 3.00 | .259 | 1.05 | 4.7 | 4.7 | 11.6 | 21.0 | 11 | 7 | 7 | 1 | 11 | 27 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 2.62 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 63 | 14 | 0 | 3 | 2 | 3.15 | .286 | 1.20 | 7.7 | 3.2 | 6.3 | 20.0 | 17 | 7 | 7 | 4 | 7 | 14 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5.25 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 50 | 12 | 0 | 2 | 0 | 2.31 | .327 | 1.46 | 11.5 | 2.5 | 9.0 | 11.2 | 14 | 4 | 3 | 1 | 3 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Donnelly, B.Donnelly, Brendan >> | 32 | 2003 | R | 40 | 9 | 0 | 0 | 0 | 1.69 | .333 | 1.50 | 7.2 | 7.2 | 8.1 | 10.2 | 8 | 2 | 2 | 0 | 8 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.60 |