| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 34 | 34 | 8 | 16 | 4.39 | .319 | 1.37 | 7.8 | 4.5 | 7.5 | 184.2 | 160 | 112 | 90 | 28 | 93 | 154 | 0 | 0 | 0 | 0 | 16 | 6 | 6 | 4.92 |
| SP | Carpenter, C.Carpenter, Chris >> | 34 | 2009 | R | 80 | 33 | 33 | 3 | 20 | 5.97 | .352 | 1.60 | 11.3 | 3.1 | 7.1 | 173.1 | 217 | 151 | 115 | 23 | 60 | 136 | 1 | 0 | 0 | 1 | 8 | 6 | 6 | 4.30 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 32 | 32 | 5 | 17 | 6.33 | .356 | 1.59 | 11.2 | 3.1 | 5.9 | 155.0 | 193 | 135 | 109 | 27 | 54 | 101 | 0 | 0 | 0 | 0 | 10 | 10 | 4 | 5.20 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 90 | 85 | 0 | 4 | 5 | 3.40 | .307 | 1.31 | 7.6 | 4.2 | 11.8 | 111.1 | 94 | 61 | 42 | 16 | 52 | 146 | 0 | 1 | 3 | 0 | 0 | 2 | 2 | 3.70 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 70 | 78 | 0 | 4 | 4 | 3.29 | .345 | 1.51 | 8.9 | 4.7 | 12.7 | 95.2 | 94 | 59 | 35 | 7 | 50 | 134 | 0 | 0 | 3 | 0 | 0 | 7 | 3 | 2.94 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 34 | 79 | 0 | 3 | 4 | 4.56 | .372 | 1.75 | 9.4 | 6.3 | 9.3 | 81.0 | 85 | 69 | 41 | 16 | 57 | 84 | 0 | 2 | 6 | 0 | 0 | 2 | 6 | 5.68 |
| RP | Quantrill, P.Quantrill, Paul >> | 33 | 2001 | R | 3 | 69 | 0 | 4 | 3 | 5.27 | .350 | 1.59 | 11.8 | 2.6 | 5.6 | 80.1 | 105 | 55 | 47 | 17 | 23 | 50 | 0 | 7 | 1 | 0 | 0 | 2 | 0 | 5.45 |
| SP | Wainwright, A.Wainwright, Adam >> | 28 | 2009 | R | 20 | 7 | 0 | 1 | 0 | 5.94 | .383 | 1.80 | 12.9 | 3.9 | 8.4 | 16.2 | 23 | 20 | 11 | 2 | 7 | 15 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.25 |