| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 28 | 28 | 15 | 10 | 3.22 | .279 | 1.14 | 8.4 | 1.9 | 5.5 | 209.2 | 194 | 83 | 75 | 16 | 44 | 128 | 10 | 0 | 0 | 3 | 19 | 6 | 4 | 3.49 |
| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 27 | 27 | 13 | 11 | 4.30 | .320 | 1.37 | 9.6 | 2.8 | 7.8 | 176.0 | 187 | 91 | 84 | 16 | 54 | 152 | 2 | 0 | 0 | 1 | 15 | 7 | 3 | 3.49 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 26 | 25 | 6 | 10 | 6.70 | .347 | 1.55 | 10.0 | 4.0 | 5.5 | 142.1 | 157 | 109 | 106 | 18 | 63 | 86 | 2 | 0 | 0 | 0 | 8 | 7 | 0 | 4.92 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 75 | 0 | 3 | 2 | 2.09 | .281 | 1.14 | 6.4 | 3.9 | 9.3 | 99.0 | 70 | 24 | 23 | 3 | 43 | 102 | 0 | 4 | 1 | 0 | 0 | 3 | 0 | 2.73 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 67 | 0 | 3 | 5 | 3.35 | .343 | 1.53 | 8.9 | 4.9 | 8.5 | 75.1 | 74 | 31 | 28 | 7 | 41 | 71 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 4.08 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 59 | 0 | 2 | 4 | 4.84 | .322 | 1.39 | 8.1 | 4.6 | 10.1 | 57.2 | 51 | 33 | 31 | 6 | 29 | 64 | 0 | 4 | 3 | 0 | 0 | 2 | 1 | 3.75 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 57 | 0 | 5 | 3 | 4.81 | .318 | 1.38 | 9.6 | 2.8 | 8.8 | 58.0 | 62 | 32 | 31 | 8 | 18 | 57 | 0 | 7 | 1 | 0 | 0 | 1 | 0 | 3.81 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 40 | 0 | 4 | 2 | 6.25 | .359 | 1.68 | 11.7 | 3.7 | 7.0 | 44.2 | 57 | 33 | 31 | 8 | 18 | 34 | 0 | 2 | 4 | 0 | 0 | 0 | 1 | 5.05 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 30 | 10 | 7 | 5 | 4.03 | .337 | 1.52 | 9.7 | 4.0 | 3.3 | 105.0 | 113 | 48 | 47 | 14 | 47 | 38 | 3 | 1 | 2 | 1 | 5 | 0 | 1 | 5.35 |