| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 28 | 28 | 13 | 10 | 3.89 | .283 | 1.17 | 8.4 | 2.2 | 8.1 | 182.2 | 169 | 91 | 79 | 27 | 44 | 164 | 4 | 0 | 0 | 0 | 17 | 3 | 6 | 3.90 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 27 | 27 | 13 | 4 | 4.03 | .277 | 1.13 | 8.0 | 2.1 | 8.0 | 172.0 | 153 | 79 | 77 | 24 | 41 | 153 | 2 | 0 | 0 | 0 | 15 | 4 | 3 | 3.82 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 27 | 27 | 14 | 7 | 3.09 | .298 | 1.23 | 6.8 | 4.3 | 8.1 | 166.0 | 125 | 62 | 57 | 13 | 80 | 149 | 0 | 0 | 0 | 0 | 18 | 6 | 5 | 3.78 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 25 | 25 | 11 | 6 | 4.38 | .295 | 1.23 | 8.9 | 2.2 | 4.6 | 158.1 | 157 | 79 | 77 | 20 | 38 | 81 | 1 | 0 | 0 | 1 | 13 | 4 | 1 | 4.42 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 26 | 26 | 8 | 9 | 5.03 | .318 | 1.37 | 9.3 | 3.1 | 5.9 | 159.1 | 164 | 99 | 89 | 24 | 55 | 104 | 3 | 0 | 0 | 0 | 13 | 4 | 2 | 4.77 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 44 | 0 | 3 | 2 | 4.34 | .371 | 1.77 | 10.0 | 6.1 | 7.8 | 37.1 | 41 | 22 | 18 | 3 | 25 | 32 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 4.35 |
| SU | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 46 | 0 | 1 | 1 | 2.22 | .288 | 1.19 | 5.3 | 5.6 | 11.1 | 48.2 | 28 | 12 | 12 | 1 | 30 | 59 | 0 | 4 | 1 | 0 | 0 | 1 | 2 | 2.75 |
| CL | Eckersley, D.Eckersley, Dennis # >> | 36 | 1990 | R | 88 | 62 | 0 | 1 | 8 | 4.58 | .292 | 1.20 | 9.3 | 1.5 | 8.8 | 59.0 | 61 | 31 | 30 | 11 | 10 | 58 | 0 | 35 | 3 | 0 | 0 | 2 | 0 | 4.07 |