| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 10 | 17 | 4.81 | .316 | 1.37 | 8.9 | 3.5 | 8.3 | 226.1 | 224 | 129 | 121 | 33 | 87 | 209 | 4 | 0 | 0 | 0 | 17 | 2 | 4 | 4.23 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 33 | 33 | 13 | 11 | 2.95 | .272 | 1.10 | 7.7 | 2.2 | 4.4 | 265.1 | 228 | 93 | 87 | 19 | 65 | 131 | 11 | 0 | 0 | 0 | 24 | 4 | 2 | 3.72 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 32 | 32 | 10 | 14 | 5.07 | .315 | 1.35 | 8.5 | 3.6 | 4.5 | 220.0 | 208 | 132 | 124 | 33 | 89 | 111 | 2 | 0 | 0 | 1 | 15 | 7 | 4 | 5.25 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 32 | 32 | 11 | 16 | 6.04 | .347 | 1.56 | 9.9 | 4.1 | 5.1 | 213.0 | 235 | 155 | 143 | 31 | 97 | 120 | 4 | 0 | 0 | 0 | 10 | 7 | 8 | 5.23 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 32 | 31 | 15 | 13 | 4.06 | .299 | 1.25 | 6.8 | 4.5 | 4.0 | 221.2 | 168 | 106 | 100 | 17 | 110 | 99 | 3 | 0 | 0 | 1 | 15 | 6 | 6 | 4.68 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 87 | 0 | 7 | 7 | 4.01 | .295 | 1.23 | 8.8 | 2.3 | 7.7 | 112.1 | 109 | 50 | 50 | 18 | 29 | 96 | 0 | 11 | 4 | 0 | 0 | 3 | 0 | 4.23 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 45 | 0 | 2 | 2 | 3.91 | .326 | 1.43 | 8.8 | 4.1 | 9.2 | 48.1 | 47 | 21 | 21 | 9 | 22 | 49 | 0 | 5 | 2 | 0 | 0 | 1 | 0 | 4.83 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 27 | 0 | 3 | 1 | 5.96 | .364 | 1.68 | 9.0 | 6.5 | 7.6 | 25.2 | 25 | 18 | 17 | 3 | 18 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.16 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 36 | 0 | 0 | 1 | 3.43 | .298 | 1.25 | 7.8 | 3.7 | 8.6 | 44.2 | 38 | 18 | 17 | 5 | 18 | 42 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.86 |