| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 38 | 38 | 13 | 11 | 4.14 | .285 | 1.19 | 8.2 | 2.5 | 5.4 | 241.1 | 219 | 116 | 111 | 24 | 67 | 145 | 7 | 0 | 0 | 2 | 20 | 3 | 3 | 3.96 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 37 | 37 | 14 | 15 | 5.10 | .330 | 1.46 | 9.5 | 3.6 | 7.7 | 217.0 | 230 | 128 | 123 | 29 | 86 | 186 | 3 | 0 | 0 | 1 | 16 | 4 | 6 | 4.27 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 31 | 30 | 14 | 7 | 3.93 | .333 | 1.50 | 8.5 | 5.1 | 3.7 | 183.1 | 172 | 87 | 80 | 13 | 103 | 76 | 2 | 0 | 0 | 0 | 19 | 0 | 1 | 4.78 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 98 | 93 | 0 | 7 | 6 | 4.08 | .300 | 1.27 | 7.3 | 4.2 | 7.8 | 90.1 | 73 | 41 | 41 | 7 | 42 | 78 | 0 | 37 | 4 | 0 | 0 | 1 | 0 | 3.71 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 92 | 101 | 0 | 5 | 3 | 2.65 | .241 | 0.92 | 5.9 | 2.5 | 9.2 | 98.2 | 64 | 30 | 29 | 7 | 27 | 100 | 0 | 1 | 3 | 0 | 0 | 3 | 3 | 2.81 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 99 | 0 | 4 | 4 | 3.39 | .268 | 1.09 | 6.5 | 3.3 | 5.4 | 95.2 | 69 | 43 | 36 | 13 | 35 | 57 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 4.72 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 85 | 0 | 4 | 3 | 2.83 | .307 | 1.33 | 6.7 | 5.4 | 7.7 | 82.2 | 61 | 27 | 26 | 4 | 49 | 70 | 0 | 4 | 4 | 0 | 0 | 0 | 1 | 3.72 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 39 | 0 | 8 | 7 | 4.97 | .335 | 1.47 | 8.7 | 4.7 | 4.8 | 54.1 | 52 | 31 | 30 | 8 | 28 | 29 | 0 | 5 | 2 | 0 | 0 | 2 | 1 | 5.52 |