| SP | Verlander, J.Verlander, Justin >> | 39 | 2022 | R | 100 | 7 | 7 | 4 | 0 | 2.82 | .309 | 1.34 | 8.8 | 3.5 | 11.5 | 44.2 | 43 | 15 | 14 | 1 | 17 | 56 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 1.91 |
| SP | Manoah, A.Manoah, Alek # >> | 24 | 2022 | R | 87 | 7 | 7 | 2 | 4 | 5.92 | .374 | 1.74 | 11.1 | 4.5 | 8.1 | 38.0 | 47 | 26 | 25 | 9 | 19 | 34 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 5.95 |
| SP | Alcantara, S.Alcantara, Sandy >> | 26 | 2022 | R | 85 | 7 | 7 | 3 | 3 | 4.40 | .325 | 1.44 | 9.2 | 3.8 | 6.2 | 45.0 | 46 | 22 | 22 | 4 | 19 | 31 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 4.04 |
| SP | Montgomery, J.Montgomery, Jordan >> | 29 | 2022 | L | 71 | 8 | 6 | 2 | 2 | 8.10 | .346 | 1.59 | 12.3 | 2.2 | 8.7 | 33.1 | 45 | 31 | 30 | 8 | 8 | 32 | 0 | 1 | 0 | 0 | 2 | 0 | 1 | 4.94 |
| RP | Iglesias, R.Iglesias, Raisel >> | 32 | 2022 | R | 87 | 18 | 0 | 1 | 0 | 2.42 | .239 | 0.90 | 7.0 | 1.2 | 9.8 | 22.1 | 17 | 7 | 6 | 2 | 3 | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.55 |
| RP | Ottavino, A.Ottavino, Adam >> | 36 | 2022 | R | 85 | 17 | 0 | 1 | 0 | 1.25 | .270 | 1.06 | 7.3 | 2.6 | 9.9 | 21.2 | 17 | 3 | 3 | 0 | 6 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 1.81 |
| RP | Barlow, S.Barlow, Scott >> | 29 | 2022 | R | 82 | 9 | 0 | 2 | 0 | 1.74 | .244 | 0.97 | 3.6 | 5.4 | 12.6 | 10.1 | 4 | 2 | 2 | 1 | 6 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.30 |
| RP | Montero, R.Montero, Rafael >> | 31 | 2022 | R | 80 | 8 | 0 | 1 | 0 | 8.64 | .375 | 1.80 | 13.5 | 3.4 | 10.1 | 8.1 | 12 | 8 | 8 | 0 | 3 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.88 |
| RP | Bednar, D.Bednar, David >> | 27 | 2022 | R | 67 | 8 | 0 | 0 | 0 | 4.50 | .318 | 1.40 | 11.7 | 0.9 | 5.4 | 10.0 | 13 | 5 | 5 | 1 | 1 | 6 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.40 |
| SU | Hentges, S.Hentges, Sam >> | 25 | 2022 | L | 92 | 9 | 0 | 1 | 0 | 3.00 | .182 | 0.67 | 5.0 | 1.0 | 19.0 | 9.0 | 5 | 3 | 3 | 1 | 1 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.56 |