| SP | Verlander, J.Verlander, Justin >> | 28 | 2011 | R | 81 | 29 | 29 | 10 | 16 | 4.49 | .312 | 1.34 | 8.7 | 3.4 | 7.0 | 206.2 | 200 | 108 | 103 | 21 | 77 | 160 | 4 | 0 | 0 | 1 | 15 | 4 | 7 | 3.95 |
| SP | Skubal, T.Skubal, Tarik # >> | 27 | 2024 | L | 74 | 29 | 28 | 10 | 11 | 3.80 | .268 | 1.08 | 7.8 | 1.9 | 8.3 | 191.2 | 166 | 86 | 81 | 18 | 41 | 177 | 1 | 0 | 0 | 0 | 16 | 3 | 3 | 3.06 |
| SP | Holton, T.Holton, Tyler >> | 28 | 2024 | L | 97 | 31 | 28 | 2 | 7 | 4.15 | .318 | 1.35 | 9.5 | 2.9 | 6.3 | 60.2 | 63 | 28 | 28 | 6 | 19 | 42 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 4.00 |
| SP | Berenguer, J.Berenguer, Juan >> | 29 | 1983 | R | 39 | 28 | 28 | 5 | 10 | 5.48 | .337 | 1.49 | 8.5 | 4.9 | 6.0 | 128.0 | 121 | 85 | 78 | 17 | 70 | 86 | 0 | 0 | 0 | 0 | 3 | 4 | 1 | 5.12 |
| SP | Hiller, J.Hiller, John >> | 25 | 1968 | L | 37 | 27 | 26 | 1 | 7 | 5.35 | .326 | 1.44 | 9.2 | 3.8 | 5.4 | 99.1 | 101 | 62 | 59 | 13 | 42 | 59 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.82 |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 80 | 86 | 0 | 11 | 10 | 5.01 | .315 | 1.37 | 7.8 | 4.5 | 9.0 | 97.0 | 84 | 55 | 54 | 13 | 49 | 97 | 0 | 3 | 5 | 0 | 0 | 1 | 0 | 4.29 |
| RP | Saucier, K.Saucier, Kevin >> | 25 | 1981 | L | 64 | 85 | 0 | 6 | 4 | 2.85 | .264 | 1.07 | 4.9 | 4.8 | 4.9 | 94.2 | 51 | 31 | 30 | 3 | 50 | 51 | 0 | 2 | 2 | 0 | 0 | 1 | 4 | 3.96 |
| RP | Alburquerque, A.Alburquerque, Al >> | 25 | 2011 | R | 61 | 83 | 0 | 3 | 3 | 4.69 | .343 | 1.52 | 8.7 | 4.9 | 11.4 | 71.0 | 69 | 37 | 37 | 5 | 39 | 90 | 0 | 1 | 3 | 0 | 0 | 3 | 3 | 3.15 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 71 | 81 | 0 | 1 | 0 | 3.91 | .310 | 1.35 | 6.0 | 6.1 | 9.0 | 69.0 | 46 | 31 | 30 | 6 | 47 | 69 | 0 | 1 | 4 | 0 | 0 | 0 | 4 | 4.17 |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 56 | 81 | 0 | 5 | 1 | 3.38 | .301 | 1.28 | 6.9 | 4.6 | 9.3 | 72.0 | 55 | 28 | 27 | 6 | 37 | 74 | 0 | 5 | 5 | 0 | 0 | 1 | 2 | 3.61 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 65 | 58 | 0 | 5 | 5 | 4.53 | .295 | 1.25 | 8.0 | 3.3 | 6.9 | 89.1 | 79 | 52 | 45 | 13 | 33 | 68 | 0 | 7 | 3 | 0 | 0 | 0 | 8 | 4.48 |