| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 94 | 11 | 11 | 7 | 1 | 2.92 | .294 | 1.19 | 8.3 | 2.5 | 9.1 | 86.1 | 79 | 30 | 28 | 4 | 24 | 87 | 7 | 0 | 0 | 2 | 7 | 5 | 1 | 2.59 |
| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 98 | 11 | 11 | 5 | 4 | 3.91 | .314 | 1.36 | 8.4 | 3.9 | 8.7 | 71.1 | 66 | 31 | 31 | 7 | 31 | 69 | 2 | 0 | 0 | 0 | 6 | 1 | 0 | 3.69 |
| SP | Youmans, F.Youmans, Floyd >> | 22 | 1986 | R | 64 | 11 | 11 | 7 | 1 | 3.62 | .331 | 1.47 | 6.9 | 6.4 | 6.3 | 74.2 | 57 | 33 | 30 | 7 | 53 | 52 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 5.01 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 82 | 11 | 11 | 6 | 4 | 3.52 | .318 | 1.40 | 9.1 | 3.5 | 5.8 | 84.1 | 85 | 34 | 33 | 4 | 33 | 54 | 5 | 0 | 0 | 1 | 7 | 0 | 3 | 3.51 |
| SP | Strasburg, S.Strasburg, Stephen >> | 24 | 2013 | R | 70 | 10 | 10 | 2 | 3 | 5.40 | .365 | 1.73 | 11.2 | 4.4 | 8.3 | 53.1 | 66 | 33 | 32 | 5 | 26 | 49 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 3.85 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 29 | 0 | 4 | 0 | 2.08 | .250 | 0.96 | 4.5 | 4.2 | 8.3 | 26.0 | 13 | 7 | 6 | 1 | 12 | 24 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.15 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 87 | 29 | 0 | 1 | 1 | 3.31 | .293 | 1.25 | 8.7 | 2.6 | 3.6 | 35.1 | 34 | 21 | 13 | 2 | 10 | 14 | 0 | 1 | 2 | 0 | 0 | 0 | 5 | 3.80 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 81 | 25 | 0 | 3 | 2 | 2.89 | .288 | 1.18 | 6.8 | 3.9 | 8.0 | 28.0 | 21 | 10 | 9 | 0 | 12 | 25 | 0 | 3 | 2 | 0 | 0 | 1 | 2 | 2.61 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 79 | 12 | 0 | 2 | 0 | 3.00 | .294 | 1.25 | 9.0 | 2.3 | 7.5 | 12.0 | 12 | 4 | 4 | 1 | 3 | 10 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.17 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 78 | 9 | 0 | 1 | 0 | 0.93 | .356 | 1.66 | 8.0 | 8.0 | 8.0 | 9.2 | 8 | 1 | 1 | 0 | 8 | 8 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.89 |