| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 23 | 23 | 10 | 8 | 3.91 | .290 | 1.21 | 8.8 | 2.1 | 8.8 | 177.1 | 173 | 78 | 77 | 20 | 42 | 173 | 8 | 0 | 0 | 1 | 14 | 2 | 1 | 3.26 |
| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 22 | 22 | 12 | 6 | 3.75 | .298 | 1.22 | 6.7 | 4.4 | 6.1 | 146.1 | 108 | 63 | 61 | 16 | 71 | 99 | 1 | 0 | 0 | 1 | 11 | 7 | 1 | 4.67 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 21 | 21 | 7 | 11 | 5.61 | .350 | 1.58 | 10.7 | 3.6 | 5.9 | 152.1 | 180 | 100 | 95 | 24 | 60 | 100 | 4 | 0 | 0 | 0 | 6 | 6 | 3 | 5.04 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 53 | 0 | 1 | 5 | 4.35 | .295 | 1.21 | 6.8 | 4.1 | 8.9 | 62.0 | 47 | 30 | 30 | 9 | 28 | 61 | 0 | 5 | 3 | 0 | 0 | 3 | 4 | 4.42 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 33 | 0 | 2 | 4 | 3.02 | .302 | 1.27 | 7.0 | 4.6 | 8.8 | 41.2 | 32 | 16 | 14 | 3 | 21 | 40 | 0 | 6 | 3 | 0 | 0 | 1 | 0 | 3.61 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 26 | 0 | 0 | 1 | 4.67 | .341 | 1.56 | 9.7 | 4.3 | 11.3 | 27.0 | 29 | 14 | 14 | 3 | 13 | 34 | 0 | 6 | 0 | 0 | 0 | 0 | 2 | 3.37 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 13 | 0 | 0 | 2 | 2.60 | .307 | 1.27 | 5.8 | 5.8 | 5.8 | 17.1 | 11 | 5 | 5 | 1 | 11 | 11 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.59 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 18 | 0 | 2 | 3 | 6.75 | .365 | 1.73 | 11.8 | 4.2 | 8.3 | 13.1 | 17 | 10 | 10 | 1 | 6 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.54 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 3 | 1 | 0 | 1 | 1.54 | .300 | 1.29 | 8.2 | 4.1 | 4.9 | 11.2 | 10 | 7 | 2 | 1 | 5 | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.45 |