| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 23 | 23 | 9 | 6 | 3.27 | .286 | 1.19 | 7.4 | 3.3 | 9.6 | 154.0 | 127 | 61 | 56 | 18 | 56 | 164 | 0 | 0 | 0 | 0 | 15 | 2 | 2 | 3.52 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 22 | 22 | 7 | 11 | 3.86 | .299 | 1.26 | 8.7 | 2.7 | 5.8 | 158.2 | 153 | 87 | 68 | 18 | 47 | 101 | 5 | 0 | 0 | 0 | 13 | 3 | 2 | 4.15 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 22 | 22 | 8 | 7 | 5.28 | .334 | 1.48 | 8.7 | 4.6 | 8.4 | 121.0 | 117 | 77 | 71 | 14 | 62 | 113 | 0 | 0 | 0 | 0 | 7 | 3 | 1 | 4.25 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 22 | 21 | 9 | 11 | 4.95 | .325 | 1.42 | 9.9 | 2.9 | 3.4 | 136.1 | 150 | 83 | 75 | 14 | 44 | 52 | 4 | 1 | 0 | 1 | 9 | 3 | 2 | 4.61 |
| RP | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 60 | 0 | 4 | 2 | 3.27 | .266 | 1.06 | 6.7 | 3.0 | 9.1 | 82.2 | 61 | 32 | 30 | 7 | 27 | 83 | 0 | 9 | 1 | 0 | 0 | 2 | 4 | 3.15 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 49 | 0 | 3 | 7 | 3.43 | .279 | 1.13 | 6.9 | 3.3 | 9.9 | 60.1 | 46 | 26 | 23 | 11 | 22 | 66 | 0 | 7 | 3 | 0 | 0 | 2 | 0 | 4.38 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 32 | 0 | 2 | 2 | 4.60 | .287 | 1.16 | 6.5 | 4.0 | 7.7 | 43.0 | 31 | 23 | 22 | 7 | 19 | 37 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 4.86 |