| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 13 | 13 | 4 | 6 | 6.01 | .318 | 1.38 | 9.1 | 3.4 | 11.0 | 67.1 | 68 | 45 | 45 | 11 | 25 | 82 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 3.85 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 13 | 13 | 3 | 3 | 5.75 | .376 | 1.81 | 11.8 | 4.5 | 6.5 | 72.0 | 94 | 47 | 46 | 9 | 36 | 52 | 1 | 0 | 0 | 0 | 5 | 0 | 1 | 4.68 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 13 | 13 | 3 | 4 | 5.97 | .347 | 1.55 | 10.7 | 3.4 | 9.4 | 75.1 | 89 | 56 | 50 | 10 | 28 | 78 | 2 | 0 | 0 | 0 | 5 | 3 | 0 | 3.89 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 65 | 14 | 12 | 4 | 2 | 5.37 | .346 | 1.57 | 11.3 | 3.0 | 7.4 | 68.2 | 85 | 42 | 41 | 14 | 23 | 56 | 1 | 1 | 0 | 0 | 4 | 1 | 0 | 5.09 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 74 | 43 | 0 | 4 | 2 | 3.46 | .264 | 1.08 | 6.1 | 3.6 | 9.9 | 52.0 | 35 | 21 | 20 | 5 | 21 | 57 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.27 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 41 | 0 | 1 | 3 | 4.03 | .347 | 1.60 | 8.8 | 5.6 | 11.8 | 51.1 | 50 | 23 | 23 | 6 | 32 | 67 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 3.78 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 35 | 0 | 5 | 3 | 3.88 | .301 | 1.25 | 7.4 | 3.9 | 10.2 | 51.0 | 42 | 22 | 22 | 6 | 22 | 58 | 0 | 3 | 3 | 0 | 0 | 2 | 1 | 3.67 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 66 | 34 | 0 | 4 | 2 | 3.19 | .278 | 1.16 | 7.1 | 3.4 | 10.1 | 42.1 | 33 | 15 | 15 | 6 | 16 | 47 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.76 |