| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 25 | 25 | 9 | 11 | 4.06 | .278 | 1.15 | 8.2 | 2.1 | 8.9 | 179.2 | 164 | 85 | 81 | 24 | 42 | 177 | 6 | 0 | 0 | 4 | 13 | 2 | 4 | 3.50 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 25 | 25 | 3 | 8 | 6.37 | .335 | 1.49 | 9.7 | 3.7 | 8.2 | 111.2 | 120 | 80 | 79 | 22 | 46 | 101 | 0 | 0 | 0 | 0 | 2 | 3 | 5 | 5.08 |
| SP | Carlton, S.Carlton, Steve † >> | 28 | 1972 | L | 69 | 25 | 24 | 14 | 8 | 2.66 | .250 | 0.98 | 5.9 | 2.9 | 7.0 | 200.0 | 130 | 66 | 59 | 23 | 65 | 156 | 17 | 0 | 0 | 3 | 19 | 5 | 6 | 3.99 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 25 | 24 | 6 | 7 | 4.65 | .331 | 1.45 | 8.9 | 4.1 | 8.4 | 155.0 | 153 | 84 | 80 | 28 | 71 | 144 | 1 | 0 | 0 | 0 | 9 | 6 | 1 | 4.98 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 87 | 73 | 0 | 3 | 3 | 5.29 | .297 | 1.24 | 9.0 | 2.1 | 10.3 | 63.0 | 63 | 41 | 37 | 12 | 15 | 72 | 0 | 2 | 1 | 0 | 0 | 2 | 3 | 4.00 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 37 | 0 | 5 | 4 | 1.76 | .259 | 1.05 | 5.3 | 4.2 | 9.9 | 41.0 | 24 | 12 | 8 | 5 | 19 | 45 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 3.78 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 53 | 0 | 0 | 7 | 2.87 | .292 | 1.24 | 7.6 | 3.7 | 9.0 | 59.2 | 50 | 21 | 19 | 9 | 24 | 59 | 0 | 3 | 2 | 0 | 0 | 0 | 6 | 4.20 |