| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 82 | 22 | 22 | 3 | 11 | 5.95 | .343 | 1.54 | 9.7 | 4.1 | 6.6 | 127.0 | 137 | 86 | 84 | 18 | 58 | 93 | 1 | 0 | 0 | 0 | 6 | 4 | 6 | 4.84 |
| SP | Severino, L.Severino, Luis >> | 23 | 2017 | R | 74 | 22 | 22 | 9 | 9 | 4.39 | .313 | 1.34 | 8.6 | 3.5 | 10.4 | 133.1 | 127 | 65 | 65 | 25 | 52 | 153 | 1 | 0 | 0 | 0 | 12 | 3 | 2 | 4.38 |
| SP | Keuchel, D.Keuchel, Dallas >> | 27 | 2015 | L | 69 | 22 | 22 | 3 | 9 | 7.12 | .362 | 1.66 | 11.4 | 3.7 | 7.3 | 122.2 | 154 | 99 | 97 | 25 | 50 | 99 | 0 | 0 | 0 | 0 | 6 | 5 | 7 | 5.39 |
| SP | Porcello, R.Porcello, Rick >> | 27 | 2016 | R | 56 | 23 | 22 | 7 | 9 | 7.46 | .376 | 1.78 | 12.8 | 3.4 | 7.3 | 126.2 | 179 | 107 | 105 | 25 | 47 | 102 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 5.15 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 57 | 0 | 7 | 8 | 2.91 | .244 | 0.96 | 6.8 | 1.9 | 11.1 | 68.0 | 51 | 22 | 22 | 8 | 14 | 84 | 0 | 15 | 4 | 0 | 0 | 1 | 0 | 2.72 |
| SU | Miller, A.Miller, Andrew >> | 30 | 2015 | L | 85 | 60 | 0 | 2 | 5 | 5.02 | .292 | 1.19 | 7.2 | 3.5 | 10.4 | 66.1 | 53 | 37 | 37 | 10 | 26 | 76 | 0 | 2 | 2 | 0 | 0 | 3 | 0 | 3.98 |
| RP | Parker, B.Parker, Blake >> | 32 | 2017 | R | 78 | 73 | 0 | 4 | 4 | 5.33 | .327 | 1.44 | 9.7 | 3.3 | 9.4 | 81.0 | 87 | 48 | 48 | 15 | 30 | 85 | 0 | 2 | 4 | 0 | 0 | 1 | 6 | 4.46 |
| RP | Feliz, N.Feliz, Neftali >> | 22 | 2010 | R | 65 | 62 | 0 | 4 | 1 | 2.81 | .261 | 1.02 | 6.3 | 3.0 | 8.9 | 73.2 | 51 | 23 | 23 | 10 | 24 | 72 | 0 | 3 | 2 | 0 | 0 | 3 | 5 | 3.92 |
| RP | Devenski, C.Devenski, Chris >> | 26 | 2017 | R | 50 | 47 | 0 | 1 | 2 | 3.81 | .266 | 1.05 | 7.0 | 2.4 | 11.6 | 59.0 | 46 | 25 | 25 | 9 | 16 | 76 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 3.32 |